Discrimination of RNA fiber structures using solid-state nanopores
RNA fibers are a class of biomaterials that can be assembled using HIV-like kissing loop
interactions. Because of the programmability of molecular design and low …
interactions. Because of the programmability of molecular design and low …
Broccoli fluorets: split aptamers as a user-friendly fluorescent toolkit for dynamic RNA nanotechnology
M Chandler, T Lyalina, J Halman… - Therapeutic RNA …, 2021 - taylorfrancis.com
806RNA aptamers selected to bind fluorophores and activate their fluorescence offer a
simple and modular way to visualize native RNAs in cells. Split aptamers which are inactive …
simple and modular way to visualize native RNAs in cells. Split aptamers which are inactive …
Tuning properties of silver nanoclusters with RNA nanoring assemblies
Combining atomically resolved DNA-templated silver nanoclusters (AgNCs) with nucleic
acid nanotechnology opens new exciting possibilities for engineering bioinorganic …
acid nanotechnology opens new exciting possibilities for engineering bioinorganic …
Simultaneous silencing of lysophosphatidylcholine acyltransferases 1-4 by nucleic acid nanoparticles (NANPs) improves radiation response of melanoma cells
RF Saito, MC Rangel, JR Halman, M Chandler… - … , Biology and Medicine, 2021 - Elsevier
Radiation induces the generation of platelet-activating factor receptor (PAF-R) ligands,
including PAF and oxidized phospholipids. Alternatively, PAF is also synthesized by the …
including PAF and oxidized phospholipids. Alternatively, PAF is also synthesized by the …
Gold nanoparticles as carriers for functional RNA nanostructures
A Graczyk, R Pawlowska, A Chworos - Bioconjugate Chemistry, 2021 - ACS Publications
Conjugates of gold nanoparticles and ribonucleic acid are particularly interesting for
biological applications to serve as therapeutics or biosensors. In this paper we present, for …
biological applications to serve as therapeutics or biosensors. In this paper we present, for …
Challenges in optimizing RNA nanostructures for large-scale production and controlled therapeutic properties
Nucleic acids have been utilized to construct an expansive collection of nanoarchitectures
varying in design, physicochemical properties, cellular processing and biomedical …
varying in design, physicochemical properties, cellular processing and biomedical …
Multifunctional role of silica in pharmaceutical formulations
Y Gao, Y Zhang, Y Hong, F Wu, L Shen, Y Wang… - AAPS …, 2022 - Springer
Due to the high surface area, adjustable surface and pore structures, and excellent
biocompatibility, nano-and micro-sized silica have certainly attracted the attention of many …
biocompatibility, nano-and micro-sized silica have certainly attracted the attention of many …
Controlled organization of inorganic materials using biological molecules for activating therapeutic functionalities
M Chandler, B Minevich, B Roark, M Viard… - … applied materials & …, 2021 - ACS Publications
Precise control over the assembly of biocompatible three-dimensional (3D) nanostructures
would allow for programmed interactions within the cellular environment. Nucleic acids can …
would allow for programmed interactions within the cellular environment. Nucleic acids can …
Nucleic acid nanoparticles at a crossroads of vaccines and immunotherapies
MA Dobrovolskaia - Molecules, 2019 - mdpi.com
Vaccines and immunotherapies involve a variety of technologies and act through different
mechanisms to achieve a common goal, which is to optimize the immune response against …
mechanisms to achieve a common goal, which is to optimize the immune response against …
Nanoparticle mediated silencing of tenascin C in hepatic stellate cells: effect on inflammatory gene expression and cell migration
Chronic liver dysfunction often begins with hepatic fibrosis. A pivotal event in the
progression of liver fibrosis and cirrhosis is hepatic stellate cell (HSC) activation and …
progression of liver fibrosis and cirrhosis is hepatic stellate cell (HSC) activation and …