Intestinal phages interact with bacteria and are involved in human diseases

H Shuwen, D Kefeng - Gut Microbes, 2022 - Taylor & Francis
Phages are the most abundant and diverse biological entities on Earth and exert specific
effects on bacterial hosts. The coexistence of phages and bacteria in the intestinal tract is …

Bacteriophages as drivers of bacterial virulence and their potential for biotechnological exploitation

K Schroven, A Aertsen, R Lavigne - FEMS microbiology reviews, 2021 - academic.oup.com
Bacteria-infecting viruses (phages) and their hosts maintain an ancient and complex
relationship. Bacterial predation by lytic phages drives an ongoing phage-host arms race …

[HTML][HTML] A preliminary study of the use of MinION sequencing to specifically detect Shiga toxin-producing Escherichia coli in culture swipes containing multiple …

HS Tunsjø, IF Ullmann, C Charnock - Scientific Reports, 2023 - nature.com
An important challenge relating to clinical diagnostics of the foodborne pathogen Shiga toxin-
producing E. coli (STEC), is that PCR-detection of the shiga-toxin gene (stx) in DNA from …

[HTML][HTML] Investigation of the Causes of Shigatoxigenic Escherichia coli PCR Positive and Culture Negative Samples

G Macori, SC McCarthy, CM Burgess, S Fanning… - Microorganisms, 2020 - mdpi.com
Molecular methods may reveal the presence of pathogens in samples through the detection
of specific target gene (s) associated with microorganisms, but often, the subsequent cultural …

[HTML][HTML] A prophage encoded ribosomal RNA methyltransferase regulates the virulence of Shiga-toxin-producing Escherichia coli (STEC)

C Gong, D Chakraborty, GB Koudelka - Nucleic Acids Research, 2024 - academic.oup.com
Shiga toxin (Stx) released by Shiga toxin producing Escherichia coli (STEC) causes life-
threatening illness. Its production and release require induction of Stx-encoding prophage …

[HTML][HTML] Valid presumption of Shiga toxin-mediated damage of developing erythrocytes in EHEC-associated hemolytic uremic syndrome

J Detzner, G Pohlentz, J Müthing - Toxins, 2020 - mdpi.com
The global emergence of clinical diseases caused by enterohemorrhagic Escherichia coli
(EHEC) is an issue of great concern. EHEC release Shiga toxins (Stxs) as their key virulence …

Everybody loves cheese: crosslink between persistence and virulence of Shiga-toxin Escherichia coli

AIL dos Santos Rosario, Y da Silva Mutz… - Critical Reviews in …, 2021 - Taylor & Francis
General cheese manufacturing involves high temperatures, fermentation and ripening steps
that function as hurdles to microbial growth. On the other hand, the application of several …

From ribosome to ribotoxins: understanding the toxicity of deoxynivalenol and Shiga toxin, two food borne toxins

M Garofalo, D Payros, F Taieb, E Oswald… - Critical Reviews in …, 2023 - Taylor & Francis
Ribosomes that synthesize proteins are among the most central and evolutionarily
conserved organelles. Given the key role of proteins in cellular functions, prokaryotic and …

[HTML][HTML] Influence of temperature and pH on induction of Shiga toxin Stx1a in Escherichia coli

VS Castro, S Ngo, K Stanford - Frontiers in Microbiology, 2023 - frontiersin.org
Shiga toxin-producing strains represent pathogenic group that is of concern in food
production. The present study evaluated forty-eight E. coli isolates (11 with intact stx gene …

[HTML][HTML] The diverse landscape of AB5-type toxins

PI Brown, A Ojiakor, AJ Chemello, CC Fowler - Engineering Microbiology, 2023 - Elsevier
ABSTRACT AB 5-type toxins are a group of secreted protein toxins that are central virulence
factors for bacterial pathogens such as Shigella dysenteriae, Vibrio cholerae, Bordetella …