The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain

ME Salliss, LV Farland, ND Mahnert… - Human reproduction …, 2022 - academic.oup.com
BACKGROUND Endometriosis is a chronic, burdensome condition that is historically
understudied. Consequently, there is a lack of understanding of the etiology of the disease …

Glutamatergic signaling along the microbiota-gut-brain axis

A Baj, E Moro, M Bistoletti, V Orlandi, F Crema… - International journal of …, 2019 - mdpi.com
A complex bidirectional communication system exists between the gastrointestinal tract and
the brain. Initially termed the “gut-brain axis” it is now renamed the “microbiota-gut-brain …

Polystyrene microplastics up-regulates liver glutamine and glutamate synthesis and promotes autophagy-dependent ferroptosis and apoptosis in the cerebellum …

K Yin, D Wang, H Zhao, Y Wang, Y Zhang, Y Liu… - Environmental …, 2022 - Elsevier
Microplastics (MPs), which are emerging environmental pollutants, remain uncertainties in
their toxic mechanism. MPs have been linked to severe liver metabolic disorders and …

Endothelial heterogeneity across distinct vascular beds during homeostasis and inflammation

A Jambusaria, Z Hong, L Zhang, S Srivastava, A Jana… - Elife, 2020 - elifesciences.org
Blood vessels are lined by endothelial cells engaged in distinct organ-specific functions but
little is known about their characteristic gene expression profiles. RNA-Sequencing of the …

Endocrine crosstalk between skeletal muscle and the brain

J Delezie, C Handschin - Frontiers in neurology, 2018 - frontiersin.org
Skeletal muscle is an essential regulator of energy homeostasis and a potent coordinator of
exercise-induced adaptations in other organs including the liver, fat or the brain. Skeletal …

The neuro-endocrinological role of microbial glutamate and GABA signaling

R Mazzoli, E Pessione - Frontiers in microbiology, 2016 - frontiersin.org
Gut microbiota provides the host with multiple functions (eg, by contributing to food
digestion, vitamin supplementation, and defense against pathogenic strains) and interacts …

Blood-brain barrier regulation in psychiatric disorders

J Kealy, C Greene, M Campbell - Neuroscience letters, 2020 - Elsevier
The blood-brain barrier (BBB) is a dynamic interface between the peripheral blood supply
and the cerebral parenchyma, controlling the transport of material to and from the brain …

Autism spectrum disorder: focus on glutamatergic neurotransmission

M Montanari, G Martella, P Bonsi… - International Journal of …, 2022 - mdpi.com
Disturbances in the glutamatergic system have been increasingly documented in several
neuropsychiatric disorders, including autism spectrum disorder (ASD). Glutamate-centered …

Changes to gut amino acid transporters and microbiome associated with increased E/I ratio in Chd8+/− mouse model of ASD-like behavior

Y Yu, B Zhang, P Ji, Z Zuo, Y Huang, N Wang… - Nature …, 2022 - nature.com
Autism spectrum disorder (ASD), a group of neurodevelopmental disorders characterized by
social communication deficits and stereotyped behaviors, may be associated with changes …

d-glutamate and Gut Microbiota in Alzheimer's Disease

CH Chang, CH Lin, HY Lane - International journal of molecular sciences, 2020 - mdpi.com
Background: An increasing number of studies have shown that the brain–gut–microbiota
axis may significantly contribute to Alzheimer's disease (AD) pathogenesis. Moreover …