[HTML][HTML] Which Factors Influence Healthy Aging? A Lesson from the Longevity Village of Bama in China
W Zhang, Q Huang, Y Kang, H Li, G Tan - Aging and Disease, 2023 - ncbi.nlm.nih.gov
A growing aging population is associated with increasing incidences of aging-related
diseases and socioeconomic burdens. Hence, research into healthy longevity and aging is …
diseases and socioeconomic burdens. Hence, research into healthy longevity and aging is …
[HTML][HTML] Gene-environment interactions within a precision environmental health framework
Understanding the complex interplay of genetic and environmental factors in disease
etiology and the role of gene-environment interactions (GEIs) across human development …
etiology and the role of gene-environment interactions (GEIs) across human development …
[HTML][HTML] Polygenic risk of hypertriglyceridemia is modified by BMI
V Esteve-Luque, M Fanlo-Maresma… - International Journal of …, 2022 - mdpi.com
Abstract Background: Genetic risk scores (GRSs) have partially improved the understanding
of the etiology of moderate hypertriglyceridemia (HTG), which until recently was mainly …
of the etiology of moderate hypertriglyceridemia (HTG), which until recently was mainly …
[HTML][HTML] Environmental Exposure Science and Human Health
AM Lavezzi, B Ramos-Molina - International journal of environmental …, 2023 - mdpi.com
Human health and environmental exposure form an inseparable binomial. Humans'
relationships with the environment are indeed a fundamental determinant of their state of …
relationships with the environment are indeed a fundamental determinant of their state of …
Gene–environment interaction analysis via deep learning
Abstract Gene–environment (G–E) interaction analysis plays an important role in studying
complex diseases. Extensive methodological research has been conducted on G–E …
complex diseases. Extensive methodological research has been conducted on G–E …
Bayesian variable selection for understanding mixtures in environmental exposures
Social and environmental stressors are crucial factors in child development. However, there
exists a multitude of measurable social and environmental factors—the effects of which may …
exists a multitude of measurable social and environmental factors—the effects of which may …
Overlapping association signals in the genetics of hair-related phenotypes in humans and their relevance to predictive DNA analysis
E Pośpiech, J Karłowska-Pik, M Kukla-Bartoszek… - Forensic Science …, 2022 - Elsevier
Genetic prediction of different hair phenotypes can help reconstruct the physical appearance
of an individual whose biological sample is analyzed in criminal and identification cases. Up …
of an individual whose biological sample is analyzed in criminal and identification cases. Up …
[HTML][HTML] Environmental pathways affecting gene expression (E. PAGE) as an R package to predict gene–environment associations
S Muralidharan, S Ali, L Yang, J Badshah, SF Zahir… - Scientific Reports, 2022 - nature.com
The purpose of this study is to manually and semi-automatically curate a database and
develop an R package that will act as a comprehensive resource to understand how …
develop an R package that will act as a comprehensive resource to understand how …
The Bayesian regularized quantile varying coefficient model
The quantile varying coefficient (VC) model can flexibly capture dynamical patterns of
regression coefficients. In addition, due to the quantile check loss function, it is robust …
regression coefficients. In addition, due to the quantile check loss function, it is robust …
Cauchy combination methods for the detection of gene–environment interactions for rare variants related to quantitative phenotypes
X Jin, G Shi - Heredity, 2023 - nature.com
The characterization of gene–environment interactions (GEIs) can provide detailed insights
into the biological mechanisms underlying complex diseases. Despite recent interest in GEIs …
into the biological mechanisms underlying complex diseases. Despite recent interest in GEIs …