[HTML][HTML] Which Factors Influence Healthy Aging? A Lesson from the Longevity Village of Bama in China

W Zhang, Q Huang, Y Kang, H Li, G Tan - Aging and Disease, 2023 - ncbi.nlm.nih.gov
A growing aging population is associated with increasing incidences of aging-related
diseases and socioeconomic burdens. Hence, research into healthy longevity and aging is …

[HTML][HTML] Gene-environment interactions within a precision environmental health framework

AA Motsinger-Reif, DM Reif, FS Akhtari, JS House… - Cell Genomics, 2024 - cell.com
Understanding the complex interplay of genetic and environmental factors in disease
etiology and the role of gene-environment interactions (GEIs) across human development …

[HTML][HTML] Polygenic risk of hypertriglyceridemia is modified by BMI

V Esteve-Luque, M Fanlo-Maresma… - International Journal of …, 2022 - mdpi.com
Abstract Background: Genetic risk scores (GRSs) have partially improved the understanding
of the etiology of moderate hypertriglyceridemia (HTG), which until recently was mainly …

[HTML][HTML] Environmental Exposure Science and Human Health

AM Lavezzi, B Ramos-Molina - International journal of environmental …, 2023 - mdpi.com
Human health and environmental exposure form an inseparable binomial. Humans'
relationships with the environment are indeed a fundamental determinant of their state of …

Gene–environment interaction analysis via deep learning

S Wu, Y Xu, Q Zhang, S Ma - Genetic epidemiology, 2023 - Wiley Online Library
Abstract Gene–environment (G–E) interaction analysis plays an important role in studying
complex diseases. Extensive methodological research has been conducted on G–E …

Bayesian variable selection for understanding mixtures in environmental exposures

DR Kowal, M Bravo, H Leong, A Bui… - Statistics in …, 2021 - Wiley Online Library
Social and environmental stressors are crucial factors in child development. However, there
exists a multitude of measurable social and environmental factors—the effects of which may …

Overlapping association signals in the genetics of hair-related phenotypes in humans and their relevance to predictive DNA analysis

E Pośpiech, J Karłowska-Pik, M Kukla-Bartoszek… - Forensic Science …, 2022 - Elsevier
Genetic prediction of different hair phenotypes can help reconstruct the physical appearance
of an individual whose biological sample is analyzed in criminal and identification cases. Up …

[HTML][HTML] Environmental pathways affecting gene expression (E. PAGE) as an R package to predict gene–environment associations

S Muralidharan, S Ali, L Yang, J Badshah, SF Zahir… - Scientific Reports, 2022 - nature.com
The purpose of this study is to manually and semi-automatically curate a database and
develop an R package that will act as a comprehensive resource to understand how …

The Bayesian regularized quantile varying coefficient model

F Zhou, J Ren, S Ma, C Wu - Computational Statistics & Data Analysis, 2023 - Elsevier
The quantile varying coefficient (VC) model can flexibly capture dynamical patterns of
regression coefficients. In addition, due to the quantile check loss function, it is robust …

Cauchy combination methods for the detection of gene–environment interactions for rare variants related to quantitative phenotypes

X Jin, G Shi - Heredity, 2023 - nature.com
The characterization of gene–environment interactions (GEIs) can provide detailed insights
into the biological mechanisms underlying complex diseases. Despite recent interest in GEIs …