Hepatocellular carcinoma (HCC) is one of the male-dominant liver diseases with poor
prognosis, although treatments for HCC have been progressing in the past decades …

Sorafenib, a multi-kinase inhibitor with antiangiogenic, antiproliferative, and proapoptotic
properties, is the first-line treatment for patients with late-stage hepatocellular carcinoma …

Hepatocellular carcinoma (HCC) is the most common type of primary hepatic malignancy.
HCC is one of the leading causes of cancer deaths worldwide. The oral multi-tyrosine kinase …

The transforming growth factor-beta (TGF-β) signaling pathway plays critical roles in the
development of various diseases. The current study investigated whether TGF-β was …

Hepatocellular carcinoma (HCC) is a type of malignant cancer. Notch signaling is aberrantly
expressed in HCC tissues with more evidence showing that this signaling plays a critical …

Neural stem cells (NSCs) are multipotent cells that have the capacity for differentiation into
the major cell types of the nervous system, ie neurons, astrocytes and oligodendrocytes …

Steatosis is the characteristic type of VPA-induced hepatotoxicity and may result in life-
threatening hepatic lesion. Approximately 61% of patients treated with VPA have been …

Liver cancer is highly malignant, has a low sensitivity to chemotherapy, and is associated
with poor patient prognosis. The last 3 years have seen the emergence of promising …

The transforming growth factor beta (TGF-β) signaling plays a critical role in immune evasion
and tumor progression. However, its modulatory influences on prognosis, tumor …

The malignant traits involved in tumor relapse, metastasis and the expansion of cancer stem-
like cells are acquired via the epithelial–mesenchymal transition (EMT) process in the tumor …