Skin wound healing shows an extraordinary cellular function mechanism, unique in nature
and involving the interaction of several cells, growth factors and cytokines. Physiological …

Animal testing has long been used in science to study complex biological phenomena that
cannot be investigated using two-dimensional cell cultures in plastic dishes. With time, it …

The critical effects that impair diabetic wound healing are characterized by poor
vascularization and severe peripheral neuropathy. Current management strategies for …

Abstract In-situ three-dimensional (3D) bioprinting has been emerging as a promising
technology designed to rapidly seal cutaneous defects according to their contour …

In the field of tissue engineering and regenerative medicine, hydrogels are used as
biomaterials to support cell attachment and promote tissue regeneration due to their unique …

The first bioprocess that occurs in response to wounding is the deterrence of local
hemorrhage. This is accomplished by platelet aggregation and initiation of the hemostasis …

Extrusion-based bioprinting, also known as 3D bioplotting, is a powerful tool for the
fabrication of tissue equivalents with spatially defined cell distribution. Even though …

Cardiovascular diseases such as myocardial infarction (MI) are among the major causes of
death worldwide. Although intramyocardial injection of hydrogels can effectively enhance …

Platelets play a crucial role in hemostasis, tissue regeneration and host defense. Based on
these settings, platelet-rich plasma (PRP) and its derivatives are therapeutically used to …

Bone healing is a dynamic process regulated by biochemical signals such as chemokines
and growth factors, and biophysical signals such as topographical and mechanical features …