The cellular uptake of free fatty acids (FFA) is followed by esterification to coenzyme A
(CoA), generating fatty acyl-CoAs that are substrates for oxidation or incorporation into …

Thioesterases are present in all living cells and perform a wide range of important biological
functions by catalysing the cleavage of thioester bonds present in a diverse array of cellular …

Phosphatidylcholine transfer protein (PC-TP; synonym StarD2) is a soluble lipid-binding
protein that transports phosphatidylcholine (PC) between cellular membranes. To better …

Intramuscular fat (IMF) is the most important evaluating indicator of chicken meat quality, the
content of which is positively correlated with tenderness, flavor, and succulence of the meat …

Meeting the complex physiological demands of mammalian life requires strict control of the
metabolism of long-chain fatty acyl-CoAs because of the multiplicity of their cellular …

Mutations in Kelch-like ECH-associated protein 1 (KEAP1) cause the aberrant activation of
nuclear factor erythroid-derived 2-like 2 (NRF2), which leads to oncogenesis and drug …

Abstract The Steroidogenic Acute Regulatory Protein-related Lipid Transfer (START) domain
is a~ 210 amino acid sequence that folds into an α/β helix-grip structure forming a …

Mercury is one heavy metal toxin that could cause severe health impairments. Mercury
exposure has become a global environmental issue. Mercury chloride (HgCl 2) is one of …

Cancer cells use acetate to support the higher demand for energy and lipid biosynthesis
during uncontrolled cell proliferation, as well as for acetylation of regulatory proteins. Acyl …

Type 2 diabetes (T2D) is characterized by pathophysiological alterations in lipid metabolism.
One strategy to understand the molecular mechanisms behind these abnormalities is to …