Mice are impaired relative to rats in place and matching-to-place learning when tests are
given in a swimming pool. The rat advantage may stem from a superior spatial ability or from …

Large, but non-pathological, individual differences in neuroanatomy of the brain exist in
rodents, which have been shown to covary with behavioral traits. In the present review, we …

Many studies have used “reverse” genetics to produce “knock-out” and transgenic mice to
explore the roles of various molecules in long-term potentiation (LTP) and spatial memory …

Four inbred strains of mice, BALB/cByJ, C3H/2Ibg, C57BL/6Ibg, and DBA/2Ibg, were tested
for their learning ability in the Morris water maze. Two forms of learning were examined: cue …

Publisher Summary This chapter discusses the phylogenetic and ontogenetic aspects of the
basal forebrain (BF) cholinergic neurons. The BF cholinergic system, consisting of a cluster …

Objectives: The basal forebrain cholinergic system is involved in cognitive processes that
require an attentive state, an increased level of arousal, and/or cortical activation associated …

How much of the remarkable variation in neuron number within a species is generated by
genetic differences, and how much is generated by environmental factors? We address this …

One function of the hippocampus is to ascertain the novelty of incoming sensations and
encode significant new information into memory. The regulation of response to repeated …

Cholinergic neurons innervating cortical structures are among the most affected neuronal
populations in Alzheimer's disease. In rodents, they express high levels of the neurotrophin …

This study examined emotionality, activity, learning and memory, as well as the influence of
emotionality and activity on learning and memory performance in C57BL/6 and DBA/2 mice …