Rodent habenulo–interpeduncular pathway expresses a large variety of uncommon nAChR subtypes, but only the α3β4 and α3β3β4 subtypes mediate acetylcholine …

SR Grady, M Moretti, M Zoli, MJ Marks… - Journal of …, 2009 - Soc Neuroscience
Recent studies suggest that the neuronal nicotinic receptors (nAChRs) present in the
habenulo–interpeduncular (Hb–IPn) system can modulate the reinforcing effect of addictive …

The habenulo-interpeduncular pathway in nicotine aversion and withdrawal

B Antolin-Fontes, JL Ables, A Görlich… - Neuropharmacology, 2015 - Elsevier
Progress has been made over the last decade in our understanding of the brain areas and
circuits involved in nicotine reward and withdrawal, leading to models of addiction that …

Subnuclear organization of the rat habenular complexes

KH Andres, MV Düring, RW Veh - Journal of Comparative …, 1999 - Wiley Online Library
The habenular complexes represent phylogenetically constant structures in the
diencephalon of all vertebrates. Available evidence suggests that this area is engaged in a …

The medial habenula: still neglected

H Viswanath, AQ Carter, PR Baldwin… - Frontiers in human …, 2014 - frontiersin.org
The habenula is a small, bilateral brain structure located at the dorsal end of the
diencephalon. This structure sends projections to the dopaminergic striatum and receives …

Differential expression and function of nicotinic acetylcholine receptors in subdivisions of medial habenula

PY Shih, SE Engle, G Oh, P Deshpande… - Journal of …, 2014 - Soc Neuroscience
Neuronal nAChRs in the medial habenula (MHb) to the interpeduncular nucleus (IPN)
pathway are key mediators of nicotine's aversive properties. In this paper, we report new …

Cholinergic elements in the zebrafish central nervous system: Histochemical and immunohistochemical analysis

D Clemente, A Porteros, E Weruaga… - Journal of …, 2004 - Wiley Online Library
Recently, the zebrafish has been extensively used for studying the development of the
central nervous system (CNS). However, the zebrafish CNS has been poorly analyzed in the …

Directional asymmetry of the zebrafish epithalamus guides dorsoventral innervation of the midbrain target

JT Gamse, YS Kuan, M Macurak, C Brösamle… - 2005 - journals.biologists.com
The zebrafish epithalamus, consisting of the pineal complex and flanking dorsal habenular
nuclei, provides a valuable model for exploring how left-right differences could arise in the …

Muscarinic M2 receptor mRNA expression and receptor binding in cholinergic and non-cholinergic cells in the rat brain: a correlative study using in situ hybridization …

MT Vilaro, KH Wiederhold, JM Palacios, G Mengod - Neuroscience, 1992 - Elsevier
The goal of the present study was to identify the cells containing mRNA coding for the m2
subtype of muscarinic cholinergic receptors in the rat brain. In situ hybridization …

Role of the dorsal medial habenula in the regulation of voluntary activity, motor function, hedonic state, and primary reinforcement

YWA Hsu, SD Wang, S Wang, G Morton… - Journal of …, 2014 - Soc Neuroscience
The habenular complex in the epithalamus consists of distinct regions with diverse neuronal
populations. Past studies have suggested a role for the habenula in voluntary exercise …

Habenula lesions cause impaired cognitive performance in rats: implications for schizophrenia

L Lecourtier, HC Neijt, PH Kelly - European Journal of …, 2004 - Wiley Online Library
Cognitive impairment is a prominent feature of schizophrenia. Currently there is no well‐
accepted explanation of the aetiology of this disorder, but recent evidence indicates that …