Signaling pathways and targeted therapy for myocardial infarction

Q Zhang, L Wang, S Wang, H Cheng, L Xu… - Signal transduction and …, 2022 - nature.com
Although the treatment of myocardial infarction (MI) has improved considerably, it is still a
worldwide disease with high morbidity and high mortality. Whilst there is still a long way to …

Salvia miltiorrhiza in Treating Cardiovascular Diseases: A Review on Its Pharmacological and Clinical Applications

J Ren, L Fu, SH Nile, J Zhang, G Kai - Frontiers in pharmacology, 2019 - frontiersin.org
Bioactive chemical constitutes from the root of Salvia miltiorrhiza classified in two major
groups, viz., liposoluble tanshinones and water-soluble phenolics. Tanshinone IIA is a major …

Phytochemistry and cardiovascular protective effects of Huang‐Qi (Astragali Radix)

H Su, S Shaker, Y Kuang, M Zhang… - Medicinal Research …, 2021 - Wiley Online Library
Abstract Huang‐Qi (Astragali Radix) is an herbal tonic widely used in China and many other
countries. It is derived from the roots of Astragalus membranaceus and A. membranaceus …

[HTML][HTML] Comprehensive review of two groups of flavonoids in Carthamus tinctorius L.

B Xian, R Wang, H Jiang, Y Zhou, J Yan… - Biomedicine & …, 2022 - Elsevier
Safflower (Carthamus tinctorius L.) is cultivated in various countries for the flavonoid
compounds it contains. These flavonoids have been used in many industries as drugs …

Application of Chinese medicine in acute and critical medical conditions

Y Luo, CZ Wang, J Hesse-Fong, JG Lin… - The American journal of …, 2019 - World Scientific
Western medicine is routinely used in developed nations as well as in Eastern countries,
where traditional medicine is frequently used by a selection of patients or family member as …

Neuroprotective effect of Danhong injection on cerebral ischemia-reperfusion injury in rats by activation of the PI3K-Akt pathway

C Feng, H Wan, Y Zhang, L Yu, C Shao, Y He… - Frontiers in …, 2020 - frontiersin.org
Many traditional Chinese medicines, including Danhong injection (DHI), can be used to treat
cerebral ischemia-reperfusion injury and have neuroprotective effects on the brain; however …

Application of carbohydrates in approved small molecule drugs: A review

H Jiang, X Qin, Q Wang, Q Xu, J Wang, Y Wu… - European Journal of …, 2021 - Elsevier
Carbohydrates are an important energy source and play numerous key roles in all living
organisms. Carbohydrates chemistry involved in diagnosis and treatment of diseases has …

Pharmacological potential of the combination of Salvia miltiorrhiza (Danshen) and Carthamus tinctorius (Honghua) for diabetes mellitus and its cardiovascular …

JO Orgah, S He, Y Wang, M Jiang, Y Wang… - Pharmacological …, 2020 - Elsevier
Metabolic syndrome, such as diabetes mellitus, obesity, atherosclerosis, and high blood
pressure (HBP), are closely linked pathophysiologically. However, current monotherapies …

[HTML][HTML] Danhong injection alleviates cerebral ischemia/reperfusion injury by improving intracellular energy metabolism coupling in the ischemic penumbra

M Zeng, H Zhou, Y He, Z Wang, C Shao, J Yin… - Biomedicine & …, 2021 - Elsevier
Danhong injection (DHI) is a compound Chinese medicine widely used in China for
treatment of ischemic cardio-cerebrovascular diseases. However, limited data are available …

[HTML][HTML] Uncovering the pharmacological mechanism of Carthamus tinctorius L. on cardiovascular disease by a systems pharmacology approach

G Yu, Z Luo, Y Zhou, L Zhang, Y Wu, L Ding… - Biomedicine & …, 2019 - Elsevier
Carthamus tinctorius L. is widely used in traditional Chinese medicines for the treatment of
cardiovascular disease. However, our current understanding of the molecular mechanisms …