Hepatocellular carcinoma (HCC) is one of the most common and lethal malignant tumors
worldwide. HCC is a complex process that is associated with several etiological factors …

Hepatocellular carcinoma (HCC), the most common type of primary liver cancer, is a leading
cause of cancer-related death worldwide. It is highly refractory to most systemic therapies …

An individual's sex has been long recognized as a key factor affecting cancer incidence,
prognosis, and treatment responses. However, the molecular basis for sex disparities in …

Importance Molecular aberrations in the phosphatidylinositol-3-kinase (PI3K) pathway drive
tumorigenesis. Frequently co-occurring alterations in hormone receptors and/or human …

Cancer with heavily economic and social burden is the hot point in the field of medical
research. Some remarkable achievements have been made; however, the exact …

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths
worldwide. Although recent advances in therapeutic approaches for treating HCC have …

The proportion of obese or diabetic population has been anticipated to increase in the
upcoming decades, which rises the prevalence of nonalcoholic fatty liver disease (NAFLD) …

Simple Summary Non-alcoholic fatty liver disease (NAFLD) is expected to become the
leading cause of hepatocellular carcinoma (HCC) in the near future. In this article, we review …

Obesity-related complications such as non-alcoholic fatty liver disease (NAFLD) and type 2
diabetes (T2D) are well-established risk factors for the development of hepatocellular …

Objective We investigated the mutational landscape of mammalian target of rapamycin
(mTOR) signalling cascade in hepatocellular carcinomas (HCCs) with chronic HBV …