Multiple nanotherapeutics have been approved for patients with cancer, but their effects on
survival have been modest and, in some examples, less than those of other approved …

Although conventional chemotherapy has been successful to some extent, the main
drawbacks of chemotherapy are its poor bioavailability, high-dose requirements, adverse …

An urgent need for early detection and diagnosis of diseases continuously pushes the
advancements of imaging modalities and contrast agents. Current challenges remain for fast …

A new era of nanomedicines that involve nucleic acids/gene therapy has been opened after
two decades in 21st century and new types of more efficient drug delivery systems (DDS) …

The lymphatic system serves an integral role in fluid homeostasis, lipid metabolism and
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …

Calcium-based (CaXs) biomaterials including calcium phosphates, calcium carbonates,
calcium silicate and calcium fluoride have been widely utilized in the biomedical field owing …

Lymph nodes (LNs) are important hubs for metastatic cell arrest and growth, immune
modulation, and secondary dissemination to distant sites through a series of mechanisms …

Calcium phosphates (CaPs) are ubiquitous in nature and vertebrate bones and teeth, and
have high biocompatibility and promising applications in various biomedical fields …

In many ways, cancer cells are different from healthy cells. A lot of tactical nano-based drug
delivery systems are based on the difference between cancer and healthy cells. Currently …

We reported a preclinical cancer vaccine that simultaneously introduced an mRNA antigen
and an immune checkpoint blocking siRNA into the antigen-presenting cells. This was …