Genetics and epigenetics of gastroenteropancreatic neuroendocrine neoplasms

A Mafficini, A Scarpa - Endocrine reviews, 2019 - academic.oup.com
Gastroenteropancreatic (GEP) neuroendocrine neoplasms (NENs) are heterogeneous
regarding site of origin, biological behavior, and malignant potential. There has been a rapid …

Pancreatic neuroendocrine tumors

J Sun - Intractable & rare diseases research, 2017 - jstage.jst.go.jp
Pancreatic neuroendocrine neoplasms (pNENs) are a heterogeneous group of tumors
including well differentiated pancreatic neuroendocrine tumors (pNETs) and …

Correlations between [68Ga]Ga-DOTA-TOC Uptake and Absorbed Dose from [177Lu]Lu-DOTA-TATE

R Bruvoll, J Blakkisrud, LT Mikalsen, J Connelly… - Cancers, 2023 - mdpi.com
Simple Summary Peptide receptor radionuclide therapy (PRRT) with [177Lu] Lu-DOTA-
TATE is used to treat gastroenteropancreatic neuroendocrine tumours (GEP-NET) by …

The neuroendocrine neoplasms of the digestive tract: diagnosis, treatment and nutrition

J Pobłocki, A Jasińska, A Syrenicz, E Andrysiak-Mamos… - Nutrients, 2020 - mdpi.com
Nuroendocrine neoplasms (NENs) are a group of rare neoplasms originating from dispersed
neuroendocrine cells, mainly of the digestive and respiratory tract, showing characteristic …

Clinical application of microRNA testing in neuroendocrine tumors of the gastrointestinal tract

C Vicentini, M Fassan, E D'Angelo, V Corbo… - Molecules, 2014 - mdpi.com
It is well documented that dysregulation of microRNAs is a hallmark of human cancers. Thus,
this family of small non-coding regulatory molecules represents an excellent source of …

Impact of liver and whole-body diffusion-weighted MRI for neuroendocrine tumors on patient management: a pilot study

F Moryoussef, L de Mestier, M Belkebir… - …, 2017 - karger.com
Background: Computed tomography scan is the current standard cross-sectional imaging
modality for neuroendocrine tumor (NET) workup. Diffusion-weighted magnetic resonance …

[HTML][HTML] Identification of the BRAF V600E mutation in gastroenteropancreatic neuroendocrine tumors

C Park, SY Ha, ST Kim, HC Kim, JS Heo, YS Park… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Genomic profiles of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are still
insufficiently understood, and the genetic alterations associated with drug responses have …

Molecular genetic studies of pancreatic neuroendocrine tumors: New therapeutic approaches

M Stevenson, KE Lines… - … and Metabolism Clinics, 2018 - endo.theclinics.com
Pancreatic neuroendocrine tumors (PNETs), which account for 1% to 2% of all pancreatic
neoplasms, are pathologically heterogeneous and consist of epithelial cells with phenotypic …

Deletion of Men1 and somatostatin induces hypergastrinemia and gastric carcinoids

S Sundaresan, AJ Kang, MM Hayes, EYK Choi… - Gut, 2017 - gut.bmj.com
Background Gastric carcinoids are slow growing neuroendocrine tumours arising from
enterochromaffin-like (ECL) cells in the corpus of stomach. Although most of these tumours …

DNA methylation profiles distinguish different subtypes of gastroenteropancreatic neuroendocrine tumors

A How-Kit, E Dejeux, B Dousset, V Renault… - …, 2015 - Taylor & Francis
Aim: Most studies have considered gastroenteropancreatic neuroendocrine tumors (GEP-
NETs) as a homogenous group of samples or distinguish only gastrointestinal from …