[HTML][HTML] The role of tricarboxylic acid cycle metabolites in viral infections

FJ Sánchez-García, CA Pérez-Hernández… - Frontiers in cellular …, 2021 - frontiersin.org
Host cell metabolism is essential for the viral replication cycle and, therefore, for productive
infection. Energy (ATP) is required for the receptor-mediated attachment of viral particles to …

Recombinant protein expression: Challenges in production and folding related matters

A Beygmoradi, A Homaei, R Hemmati… - International Journal of …, 2023 - Elsevier
Protein folding is a biophysical process by which proteins reach a specific three-dimensional
structure. The amino acid sequence of a polypeptide chain contains all the information …

STALLION: a stacking-based ensemble learning framework for prokaryotic lysine acetylation site prediction

S Basith, G Lee, B Manavalan - Briefings in Bioinformatics, 2022 - academic.oup.com
Protein post-translational modification (PTM) is an important regulatory mechanism that
plays a key role in both normal and disease states. Acetylation on lysine residues is one of …

Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis

S Park, D Mossmann, Q Chen, X Wang, E Dazert… - Molecular cell, 2022 - cell.com
Acetyl-coenzyme A (acetyl-CoA) plays an important role in metabolism, gene expression,
signaling, and other cellular processes via transfer of its acetyl group to proteins and …

Dual lysine and N‐terminal acetyltransferases reveal the complexity underpinning protein acetylation

WV Bienvenut, A Brünje, JB Boyer… - Molecular Systems …, 2020 - embopress.org
Protein acetylation is a highly frequent protein modification. However, comparatively little is
known about its enzymatic machinery. N‐α‐acetylation (NTA) and ε‐lysine acetylation (KA) …

[HTML][HTML] Widespread protein lysine acetylation in gut microbiome and its alterations in patients with Crohn's disease

X Zhang, Z Ning, J Mayne, Y Yang, SA Deeke… - Nature …, 2020 - nature.com
Lysine acetylation (Kac), an abundant post-translational modification (PTM) in prokaryotes,
regulates various microbial metabolic pathways. However, no studies have examined …

Acetylation of lactate dehydrogenase negatively regulates the acidogenicity of Streptococcus mutans

Q Ma, Y Pan, Y Chen, S Yu, J Huang, Y Liu, T Gong… - Mbio, 2022 - Am Soc Microbiol
Lysine acetylation, a ubiquitous and dynamic regulatory posttranslational modification
(PTM), affects hundreds of proteins across all domains of life. In bacteria, lysine acetylation …

Green approach and strategies for wastewater treatment using bioelectrochemical systems: A critical review of fundamental concepts, applications, mechanism, and …

M Al-Sahari, A Al-Gheethi, RMSR Mohamed, E Noman… - Chemosphere, 2021 - Elsevier
Millions of litters of multifarious wastewater are directly disposed into the environment
annually to reduce the processing costs leading to eutrophication and destroying the clean …

[HTML][HTML] Mitochondrial fission as a therapeutic target for metabolic diseases: insights into antioxidant strategies

T Yu, L Wang, L Zhang, PA Deuster - Antioxidants, 2023 - mdpi.com
Mitochondrial fission is a crucial process in maintaining metabolic homeostasis in normal
physiology and under conditions of stress. Its dysregulation has been associated with …

Identifying clinically relevant bacteria directly from culture and clinical samples with a handheld mass spectrometry probe

SC Povilaitis, A Chakraborty, LM Kirkpatrick… - Clinical …, 2022 - academic.oup.com
Background Rapid identification of bacteria is critical to prevent antimicrobial resistance and
ensure positive patient outcomes. We have developed the MasSpec Pen, a handheld mass …