Ascorbic acid, as a one of the basic exogenous vitamins, occurs in the body in the form of
ascorbate, known for its strong antioxidant and anti-inflammatory properties. The presented …

Objectives: The effects of vitamin C administration on clinical outcome in critically ill patients
remain controversial. Data Sources: Online databases were searched up to October 1, 2018 …

Extracorporeal circulation (ECC) systems, including cardiopulmonary bypass, and
extracorporeal membrane oxygenation have been an irreplaceable part of the …

The pleiotropic biochemical and antioxidant functions of vitamin C have sparked recent
interest in its application in intensive care. Vitamin C protects important organ systems …

Background: Cardiac surgery is associated with oxidative stress and systemic inflammation,
which both contribute to postoperative organ dysfunction. Vitamin C is a pleiotropic …

Objectives Coronary artery bypass graft (CABG) surgery has been reported to be associated
with lower postoperative plasma antioxidant and zinc levels. We hypothesized that …

Objective: To evaluate the effect of high-dose vitamin C on cardiac reperfusion injury and
plasma levels of creatine kinase-muscle/brain (CK-MB), troponin I, and lactate …

Worldwide, the prevalence of surgery under general anesthesia has significantly increased,
both because of modern anesthetic and pain-control techniques and because of better …

Background Coronary artery bypass graft (CABG) surgery with cardiopulmonary bypass
(CPB) triggers an inflammatory reaction, leading to the development of myocardial damage …

Objectives Acute kidney injury (AKI) is associated with higher perioperative mortality and
morbidity. Oxidative stress has been proposed as a cause of postoperative AKI. Ascorbic …