Immune mechanisms of pulmonary fibrosis with bleomycin

Y Ishida, Y Kuninaka, N Mukaida, T Kondo - International journal of …, 2023 - mdpi.com
Fibrosis and structural remodeling of the lung tissue can significantly impair lung function,
often with fatal consequences. The etiology of pulmonary fibrosis (PF) is diverse and …

Progress in understanding and treating idiopathic pulmonary fibrosis: Recent insights and emerging therapies

H Guo, J Sun, S Zhang, Y Nie, S Zhou… - Frontiers in …, 2023 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a long-lasting, continuously advancing, and irrevocable
interstitial lung disorder with an obscure origin and inadequately comprehended …

[HTML][HTML] The role of matrix metalloproteinase 9 in fibrosis diseases and its molecular mechanisms

Y Wang, L Jiao, C Qiang, C Chen, Z Shen… - Biomedicine & …, 2024 - Elsevier
Fibrosis is a process of tissue repair that results in the slow creation of scar tissue to replace
healthy tissue and can affect any tissue or organ. Its primary feature is the massive …

Effect and safety of mesenchymal stem cells for patients with COVID‐19: Systematic review and meta‐analysis with trial sequential analysis

Z Zhang, S Shao, X Liu, Z Tong - Journal of Medical Virology, 2023 - Wiley Online Library
The objective of this study was to assess whether mesenchymal stem cells (MSCs) therapy
could offer survival advantages for patients with novel coronavirus disease 2019 (COVID …

Advanced 3D In Vitro Lung Fibrosis Models: Contemporary Status, Clinical Uptake, and Prospective Outlooks

N Jain, BL Shashi Bhushan, M Natarajan… - ACS Biomaterials …, 2024 - ACS Publications
Fibrosis has been characterized as a global health problem and ranks as one of the primary
causes of organ dysfunction. Currently, there is no cure for pulmonary fibrosis, and limited …

Translational potential of mesenchymal stem cells in regenerative therapies for human diseases: challenges and opportunities

S Zhidu, T Ying, J Rui, Z Chao - Stem Cell Research & Therapy, 2024 - Springer
Advances in stem cell technology offer new possibilities for patients with untreated diseases
and disorders. Stem cell-based therapy, which includes multipotent mesenchymal stem cells …

[HTML][HTML] Therapeutic potential of human stem cell-derived extracellular vesicles in idiopathic pulmonary fibrosis

KS Lee, SH Yeom, MK Kim, CH Woo, YC Choi… - Extracellular …, 2024 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a lethal and chronic lung disease that occurs due to
persistent epithelial cell injury and abnormal extracellular matrix (ECM) deposition …

Mesenchymal Stem Cell-Derived Exosomes Attenuate Murine Cytomegalovirus-Infected Pneumonia via NF-κB/NLRP3 Signaling Pathway

F Chen, Z Chen, HT Wu, XX Chen, P Zhan, ZY Wei… - Viruses, 2024 - mdpi.com
Reactivation and infection with cytomegalovirus (CMV) are frequently observed in recipients
of solid organ transplants, bone marrow transplants, and individuals with HIV infection. This …

Adipose-derived mesenchymal stem cell therapy for reverse bleomycin-induced experimental pulmonary fibrosis

X Zhao, J Wu, R Yuan, Y Li, Q Yang, B Wu, X Zhai… - Scientific Reports, 2023 - nature.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive respiratory disease. Arguably,
the complex interplay between immune cell subsets, coupled with an incomplete …

Alleviation of pulmonary fibrosis by the dual PPAR agonist saroglitazar and breast milk mesenchymal stem cells via modulating TGFß/SMAD pathway

SH Attia, SF Saadawy, SM El-Mahroky… - Naunyn-Schmiedeberg's …, 2024 - Springer
Pulmonary fibrosis (PF) is a complex disorder with high morbidity and mortality. Limited
efficacies of the available drugs drive researchers to seek for new therapies. Saroglitazar …