Systemic sclerosis (SSc) is a complex disease characterized by early microvascular
abnormalities, immune dysregulation and chronic inflammation, and subsequent fibrosis of …

The thioredoxin (Trx) system is one of the central antioxidant systems in mammalian cells,
maintaining a reducing environment by catalyzing electron flux from nicotinamide adenine …

Autoantibodies directed against a variety of nuclear, cytoplasmic and extracellular
autoantigens are a serological hallmark of systemic sclerosis. This review provides an …

Systemic sclerosis is an autoimmune disorder characterized by inflammation and a
progressive fibrosis affecting the skin and visceral organs. Over the last two decades, it …

A key challenge to the clinical implementation of decellularized scaffold-based tissue
engineering lies in understanding the process of removing cells and immunogenic material …

Systemic sclerosis (SS c) is a rare disorder of the connective tissue characterized by fibrosis
of the skin, skeletal muscles and visceral organs. Additional manifestations include …

The diagnosis of interstitial lung disease (ILD) requires meticulous evaluation for an
underlying connective tissue disease (CTD), with major implications for prognosis and …

Autoimmune diseases (ADs) such as Sjögren's syndrome, Kawasaki disease, and systemic
sclerosis are characterized by chronic inflammation, oxidative stress, and autoantibodies …

Peroxiredoxins (Prx) are a family of anti‐oxidants that protect cells from metabolically
produced reactive oxygen species (ROS). The presence of these enzymes in the …

Autoantibodies in systemic sclerosis are associated with demographic, diagnostic,
pathological, and prognostic features of the disease. Emerging research on the pathogenic …