The external exposome and food allergy

TP Moran - Current allergy and asthma reports, 2020 - Springer
Abstract Purpose of Review The recent increase in childhood food allergy prevalence
strongly suggests that environmental exposures are contributing to food allergy …

[HTML][HTML] When the allergy alarm bells toll: The role of Toll-like receptors in allergic diseases and treatment

M Wenger, S Grosse-Kathoefer, A Kraiem… - Frontiers in Molecular …, 2023 - ncbi.nlm.nih.gov
Toll-like receptors of the human immune system are specialized pathogen detectors able to
link innate and adaptive immune responses. TLR ligands include among others bacteria …

Involvement of TLR2 and TLR4 in inflammatory immune responses induced by fine and coarse ambient air particulate matter

J Shoenfelt, RJ Mitkus, R Zeisler… - Journal of leukocyte …, 2009 - academic.oup.com
Fine and coarse air pollution particles signal macrophage activation via differential
utilization of Toll-like receptors (TLR) 2 and TLR4 but shared use of the MyD88 signaling …

Draft genome of the scabies mite

SD Rider, MS Morgan, LG Arlian - Parasites & vectors, 2015 - Springer
Background The disease scabies, caused by the ectoparasitic mite, Sarcoptes scabiei,
causes significant morbidity in humans and other mammals worldwide. However, there is …

Sargassum horneri (Turner) inhibit urban particulate matter-induced inflammation in MH-S lung macrophages via blocking TLRs mediated NF-κB and MAPK activation

KKA Sanjeewa, TU Jayawardena, SY Kim… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Sargassum horneri is a nutrient rich edible brown
seaweed with numerous biological properties found in shallow coastal areas of Korean …

Invariant NKT cells are required for airway inflammation induced by environmental antigens

G Wingender, P Rogers, G Batzer, MS Lee… - Journal of Experimental …, 2011 - rupress.org
Invariant NKT cells (i NKT cells) are a unique subset of T lymphocytes that rapidly carry out
effector functions. In this study, we report that a majority of sterile house dust extracts (HDEs) …

Indoor dust acts as an adjuvant to promote sensitization to peanut through the airway

JM Smeekens, RM Immormino… - Clinical & …, 2019 - Wiley Online Library
Background There is growing evidence that environmental peanut exposure through non‐
oral routes, including the skin and respiratory tract, can result in peanut sensitization …

Scientific rationale for the Finnish Allergy Programme 2008–2018: emphasis on prevention and endorsing tolerance

LC Von Hertzen, J Savolainen, M Hannuksela… - Allergy, 2009 - Wiley Online Library
In similarity to many other western countries, the burden of allergic diseases in Finland is
high. Studies worldwide have shown that an environment rich in microbes in early life …

Microbial content of drinking water in Finnish and Russian Karelia–implications for atopy prevalence

L Von Hertzen, T Laatikainen, T Pitkänen, T Vlasoff… - Allergy, 2007 - Wiley Online Library
Background and aim: The influence of microbial quality of drinking water from different
sources on the occurrence of atopy has been poorly examined. This study was undertaken …

[HTML][HTML] Bioaerosol exposure and in vitro activation of toll-like receptors in a Norwegian waste sorting plant

E Eriksen, P Graff, I Pedersen, A Straumfors… - Safety and Health at …, 2022 - Elsevier
Background The global shift toward greener societies demands new technologies and work
operations in the waste-management sector. However, progressive industrial methods do …