[HTML][HTML] The secretion profile of mesenchymal stem cells and potential applications in treating human diseases

Y Han, J Yang, J Fang, Y Zhou, E Candi… - … and Targeted Therapy, 2022 - nature.com
Mesenchymal stromal/stem cells (MSCs) possess multi-lineage differentiation and self-
renewal potentials. MSCs-based therapies have been widely utilized for the treatment of …

Isolation, cultivation, and characterization of human mesenchymal stem cells

D Mushahary, A Spittler, C Kasper, V Weber… - Cytometry Part …, 2018 - Wiley Online Library
Mesenchymal stem cells (MSC) exhibit a high self‐renewal capacity, multilineage
differentiation potential and immunomodulatory properties. This set of exceptional features …

[HTML][HTML] Exosomes derived from human umbilical cord blood mesenchymal stem cells stimulate regenerative wound healing via transforming growth factor-β receptor …

Y Zhang, Y Pan, Y Liu, X Li, L Tang, M Duan… - Stem cell research & …, 2021 - Springer
Background Scar formation is a common consequence of skin wound healing, and no
effective treatment exists. Umbilical cord blood mesenchymal stem cells (UCB-MSCs) can …

Umbilical cord-derived mesenchymal stem cell-derived exosomal microRNAs suppress myofibroblast differentiation by inhibiting the transforming growth factor-β …

S Fang, C Xu, Y Zhang, C Xue, C Yang… - Stem cells …, 2016 - academic.oup.com
Excessive scar formation caused by myofibroblast aggregations is of great clinical
importance during skin wound healing. Studies have shown that mesenchymal stem cells …

[HTML][HTML] Therapeutic use of mesenchymal stromal cells: the need for inclusive characterization guidelines to accommodate all tissue sources and species

A Wright, ML Arthaud-Day, ML Weiss - Frontiers in cell and …, 2021 - frontiersin.org
Following their discovery over 50 years ago, mesenchymal stromal cells (MSCs) have
become one of the most studied cellular therapeutic products by both academia and industry …

[HTML][HTML] Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling

L Wang, L Hu, X Zhou, Z Xiong, C Zhang… - Scientific Reports, 2017 - nature.com
Scar formation is an intractable medical problem that appears after skin wounds have
healed. Recent research has shown that exosomes secreted by human adipose …

Exosomes Derived from Akt-Modified Human Umbilical Cord Mesenchymal Stem Cells Improve Cardiac Regeneration and Promote Angiogenesis via Activating …

J Ma, Y Zhao, L Sun, X Sun, X Zhao… - Stem cells …, 2017 - academic.oup.com
We have previously demonstrated the cardioprotective effects of exosomes derived from
mesenchymal stem cells (MSCs). It is well known that the activation of Akt is involved in stem …

[HTML][HTML] A comparative analysis of multipotent mesenchymal stromal cells derived from different sources, with a focus on neuroregenerative potential

Y Petrenko, I Vackova, K Kekulova, M Chudickova… - Scientific reports, 2020 - nature.com
Multipotent mesenchymal stromal cells (MSCs) can be considered an accessible therapeutic
tool for regenerative medicine. Here, we compared the growth kinetics, immunophenotypic …

Exosomes from human umbilical cord mesenchymal stem cells enhance fracture healing through HIF‐1α‐mediated promotion of angiogenesis in a rat model of …

Y Zhang, Z Hao, P Wang, Y Xia, J Wu, D Xia… - Cell …, 2019 - Wiley Online Library
Objectives Exosomes, as important players in intercellular communication due to their ability
to transfer certain molecules to target cells, are believed to take similar effects in promoting …

[HTML][HTML] Different populations and sources of human mesenchymal stem cells (MSC): a comparison of adult and neonatal tissue-derived MSC

R Hass, C Kasper, S Böhm, R Jacobs - Cell Communication and Signaling, 2011 - Springer
The mesenchymal stroma harbors an important population of cells that possess stem cell-
like characteristics including self renewal and differentiation capacities and can be derived …