Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mental ability
development and interrupts neurocognitive function. This neuropathological condition is …

Medicinal plants have been used for years as a source of food, spices, and, in traditional
medicine, as a remedy to numerous diseases. Piper nigrum, belonging to the family …

Piper species are aromatic plants used as spices in the kitchen, but their secondary
metabolites have also shown biological effects on human health. These plants are rich in …

Abstract According to the Alzheimer Association Report (2017), Alzheimer's disease (AD) is
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …

The nervous system is a crucial component of the body and damages to this system, either
by of injury or disease, can result in serious or potentially lethal consequences. Restoring …

CNS disorders are on the rise despite advancements in our understanding of their
pathophysiological mechanisms. A major hurdle to the treatment of these disorders is the …

Piperine is the major bio‐active component of pepper, which imparts pungency and biting
taste to it. This naturally occurring alkaloid has numerous demonstrated health effects and …

Since the application of chitosan magnetic cationic microspheres in brain drug delivery by
Gallo in 1993, chitosan has been extensively studied in brain drug delivery. As the only …

Most of the available drugs are usually administered orally (eg in tablets or capsules) or by
parenteral injection in the case of substances being destroyed in the gastric environment or …

Black pepper is an autoicous and decorous vine cultivated and harvested in tropical regions
of Sri Lanka and India. Black pepper is one of the most commonly consumed spices, and its …