Assessment of adverse reactions to α-lipoic acid containing dietary supplements through spontaneous reporting systems

M Gatti, I Ippoliti, E Poluzzi, IC Antonazzo, PA Moro… - Clinical Nutrition, 2021 - Elsevier
Background & aims Alpha-lipoic acid (ALA)-containing dietary supplements are widely used
in clinical practice, although their safety assessment is under-investigated. We characterize …

Lipoic acid rejuvenates aged intestinal stem cells by preventing age‐associated endosome reduction

G Du, Y Qiao, Z Zhuo, J Zhou, X Li, Z Liu, Y Li… - EMBO …, 2020 - embopress.org
The age‐associated decline of adult stem cell function is closely related to the decline in
tissue function and age‐related diseases. However, the underlying mechanisms that …

Aging-related disorders and mitochondrial dysfunction: a critical review for prospect mitoprotective strategies based on mitochondrial nutrient mixtures

G Pagano, FV Pallardó, A Lyakhovich, L Tiano… - International Journal of …, 2020 - mdpi.com
A number of aging-related disorders (ARD) have been related to oxidative stress (OS) and
mitochondrial dysfunction (MDF) in a well-established body of literature. Most studies …

Alpha-lipoic acid as a nutritive supplement for humans and animals: an overview of its use in dog food

RM Anthony, JM MacLeay, KL Gross - Animals, 2021 - mdpi.com
Simple Summary A review of human and animal studies involving alpha-lipoic acid
supplementation was conducted to determine the utility of alpha-lipoic acid in dog food. The …

Protein‐Sparing Effect of α‐Lipoic Acid in Diets with Different Protein/Carbohydrate Ratios for the Oriental River Prawn, Macrobrachium nipponense

S Li, J Wang, Y Xiong, J Zheng, D Zhou… - Aquaculture …, 2023 - Wiley Online Library
Carbohydrates are commonly used in aquaculture feed because they are the cheapest
energy source. Promoting carbohydrate catabolism for energy production can increase the …

Serum Metabolomics Reveals Underlying Mechanisms of Cholesterol‐Lowering Effects of Oat Consumption: A Randomized Controlled Trial in a Mildly …

D Xu, S Wang, M Feng, V Shete, Y Chu… - Molecular nutrition & …, 2021 - Wiley Online Library
Introduction The purpose of this study is to examine the effects of oat supplementation on
serum lipid in a population of adults with mild hypercholesterolemia and reveal the …

Quercetin actions on lipid profiles in overweight and obese individuals: a systematic review and meta-analysis

W Guo, X Gong, M Li - Current pharmaceutical design, 2019 - ingentaconnect.com
Background: The lipid profile is associated with metabolic diseases in overweight and obese
individuals. Quercetin treatment is suggested to reduce the risk factors for obesity. Objective …

Effect of alpha-lipoic acid supplementation on endothelial function and cardiovascular risk factors in overweight/obese youths: a double-blind, placebo-controlled …

L Tromba, FM Perla, G Carbotta, C Chiesa, L Pacifico - Nutrients, 2019 - mdpi.com
Endothelial dysfunction is recognized as an early sign of systemic atherosclerosis, and it
represents a therapeutic target to prevent long-term cardiovascular (CV) consequences …

Metabolic effects of α-lipoic acid supplementation in pre-diabetics: a randomized, placebo-controlled pilot study

LE Gosselin, L Chrapowitzky, TC Rideout - Food & function, 2019 - pubs.rsc.org
Supplementation of health promoting nutraceuticals may be an effective adjunct strategy
with other lifestyle and drug approaches to impede disease progression in prediabetic …

Combination Therapy of Alpha-Lipoic Acid, Gliclazide and Ramipril Protects Against Development of Diabetic Cardiomyopathy via Inhibition of TGF-β/Smad Pathway

GJ Dugbartey, QL Wonje, KK Alornyo… - Frontiers in …, 2022 - frontiersin.org
Background: Diabetic cardiomyopathy (DCM) is a major long-term complication of diabetes
mellitus, accounting for over 20% of annual mortality rate of diabetic patients globally …