A neuroimmune crosstalk is involved in somatic and visceral pathological pain including
inflammatory and neuropathic components. Apart from microglia essential for spinal and …

Ischemic stroke is the second cause of mortality and the first cause of long-term disability
constituting a serious socioeconomic burden worldwide. Approved treatments include …

Functional recovery following a spinal cord injury (SCI) is challenging. Traditional drug
therapies focus on the suppression of immune responses; however, strategies for alleviating …

Spinal Cord Injury (SCI) is a common neurological disorder with devastating psychical and
psychosocial sequelae. The majority of patients after SCI suffer from permanent disability …

Emerging evidence has shown an imbalance in M1/M2 macrophage polarization to play an
essential role in osteoarthritis (OA) progression. However, the underlying mechanistic basis …

TcpC is a multifunctional virulence factor of Uropathogenic Escherichia coli (UPEC).
Macrophages can differentiate into two different subsets M1 and M2 that play distinct roles in …

Spinal cord injury (SCI) is a catastrophic condition with high morbidity and mortality that still
lacks effective therapeutic strategies. It is well known that the most important stage in SCI …

It is often difficult to regain neurological function following spinal cord injury (SCI).
Neuroinflammation is thought to be responsible for this failure. Regulating the inflammatory …

Spinal cord injury (SCI) causes tremendous harm to a patient's physical, mental, and
financial health. Moreover, recovery of SCI is affected by many factors, inflammation is one …

Neuroinflammation is a key factor of the pathology of various neurological diseases (brain
injury, depression, neurodegenerative diseases). It is a complex and orderly process that …