Circulating microparticles in patients with antiphospholipid antibodies: characterization and associations

S Chaturvedi, E Cockrell, R Espinola, L Hsi, S Fulton… - Thrombosis research, 2015 - Elsevier
The antiphospholipid syndrome is characterized by venous or arterial thrombosis and/or
recurrent fetal loss in the presence of circulating antiphospholipid antibodies. These …

Annexin A5 polymorphism (− 1C→ T) and the presence of anti-annexin A5 antibodies in the antiphospholipid syndrome

B de Laat, RHWM Derksen, IJ Mackie… - Annals of the …, 2006 - ard.bmj.com
Background: Annexin A5 is thought to have a role in the pathophysiology of the
antiphospholipid syndrome (APS)—a syndrome characterised by recurrent thrombosis and …

Inflammatory response and the endothelium

PL Meroni, MO Borghi, E Raschi, D Ventura… - Thrombosis …, 2004 - Elsevier
Antiphospholipid-mediated endothelium perturbation plays a role in antiphospholipid
syndrome (APS)-associated vasculopathy. Antiphospholipid antibodies activate …

The antiphospholipid syndrome

JH Rand - Annual review of medicine, 2003 - annualreviews.org
The antiphospholipid (aPL) antibody syndrome is an autoimmune condition in which
vascular thrombosis and/or recurrent pregnancy losses occur in patients with laboratory …

Annexin A2, autoimmunity, anxiety and depression

R Weiss, A Bitton, MB Shimon, SE Goldman… - Journal of …, 2016 - Elsevier
Objectives Antiphospholipid syndrome (APS) is associated with neurological manifestations
and one of the novel autoantigens associated with this disease is Annexin A2 (ANXA2). In …

CNS dysfunction in the antiphospholipid syndrome

A Katzav, J Chapman, Y Shoenfeld - Lupus, 2003 - journals.sagepub.com
Though many neurological deficits have been described in the antiphospholipid syndrome
(APS), only stroke is well establishedand accepted as a diagnosticcriterion in this disease …

[HTML][HTML] Pathophysiological mechanisms in antiphospholipid syndrome

BE Harper, R Wills, SS Pierangeli - International journal of clinical …, 2011 - ncbi.nlm.nih.gov
Antiphospholipid syndrome is a systemic autoimmune disease associated with thrombosis
and recurrent fetal loss in the setting of detectable antiphospholipid (aPL) antibodies. The …

[HTML][HTML] Anti-β2-GPI Antibodies Induce Endothelial Cell Expression of Tissue Factor by LRP6 Signal Transduction Pathway Involving Lipid Rafts

G Riitano, A Capozzi, S Recalchi, D Caissutti, A Longo… - Cells, 2022 - mdpi.com
In this study we analyzed whether anti-β2-GPI antibodies from patients with APS induce the
endothelial cell expression of Tissue Factor (TF) by a LRP6 signal transduction pathway …

Annexin A2: biology and relevance to the antiphospholipid syndrome

E Cockrell, RG Espinola, KR McCrae - Lupus, 2008 - journals.sagepub.com
Antiphospholipid antibodies (aPL), the majority of which are directed against β2-
glycoprotein I (β2GPI), are associated with an increased incidence of venous and arterial …

Antiphospholipid antibodies and renal involvement

A Gigante, ML Gasperini, R Cianci, B Barbano… - American Journal of …, 2009 - karger.com
Antiphospholipid antibodies are a heterogeneous group of autoantibodies associated with
the hypercoagulable state affecting all vascular districts with thrombosis named …