The antiphospholipid syndrome

JH Rand - ASH Education Program Book, 2007 - ashpublications.org
The antiphospholipid syndrome (APS) is an autoimmune thrombophilic condition that is
marked by the presence of antibodies that recognize phospholipid-binding proteins. The …

Updating on the pathogenic mechanisms 5 of the antiphospholipid antibodies-associated pregnancy loss

PL Meroni, M Gerosa, E Raschi, S Scurati… - Clinical Reviews in …, 2008 - Springer
Anti-phospholipid antibodies (aPL) are risk factor for recurrent pregnancy loss and
obstetrical complications. The mechanisms of aPL-mediated pregnancy failure are still a …

Tissue factor over-expression in platelets of patients with anti-phospholipid syndrome: induction role of anti-β2-GPI antibodies

A Capozzi, V Manganelli, G Riitano… - Clinical & …, 2019 - academic.oup.com
Anti-phospholipid syndrome (APS) is characterized by arterial and/or venous thrombosis
and pregnancy morbidity. It is well known that in these patients thrombosis may be the result …

What is antiphospholipid syndrome?

D Erkan, MD Lockshin - Current rheumatology reports, 2004 - Springer
The description of antiphospholipid syndrome (APS) is vascular thrombosis and/or
pregnancy morbidity occurring in persons with antiphospholipid antibodies (aPL). However …

Annexin A5 in cardiovascular disease and systemic lupus erythematosus

A Cederholm, J Frostegård - Immunobiology, 2005 - Elsevier
Atherosclerosis, a major cause of disease and death from cardiovascular disease (CVD), is
an inflammatory disease characterized by T cell and monocyte/macrophage infiltration in the …

Infections and the antiphospholipid syndrome

M García-Carrasco, C Galarza-Maldonado… - Clinical reviews in …, 2009 - Springer
Currently, the origin of autoimmune diseases is considered to be multifactorial. Genetic
predisposition, immune system malfunction or even backfire, hormonal regulation, and …

Thrombosis risk in systemic lupus erythematosus: the role of thrombophilic risk factors

KK Sallai, E Nagy, I Bodó, A Mohl… - Scandinavian journal of …, 2007 - Taylor & Francis
Objectives: Thromboembolic episodes are frequent manifestations of systemic lupus
erythematosus (SLE). Although the presence of anti‐phospholipid antibodies (aPL) is known …

New treatments for antiphospholipid syndrome

D Erkan, MD Lockshin - Rheumatic Disease Clinics, 2006 - rheumatic.theclinics.com
The definition of antiphospholipid syndrome (APS), as shown in Box 1, is vascular
thromboses or pregnancy morbidity occurring in persons who have one or more of a family …

The pathogenesis of obstetric APS: a 2023 update

C Mineo, PW Shaul, BL Bermas - Clinical Immunology, 2023 - Elsevier
The antiphospholipid syndrome (APS) is an autoimmune disease characterized by the
persistent presence of antibodies directed against phospholipids and phospholipid-binding …

Acquired and inherited thrombophilia disorders in pregnancy

SS Pierangeli, B Leader, G Barilaro… - Obstetrics and …, 2011 - obgyn.theclinics.com
The most common acquired thrombophilia is the antiphospholipid syndrome (APS). Nigel
Harris first used the term antiphospholipid syndrome in 1986 1 to refer to what is now a well …