Abstract Background Most investigations on MutY human homolog (MYH)-associated
polyposis (MAP) have been conducted in Western countries. Limited data on MAP in Asia …

Background The Mutyh DNA glycosylase is involved in the repair of oxidized DNA bases.
Mutations in the human MUTYH gene are responsible for colorectal cancer in familial …

MUTYH-associated polyposis (MAP) was first described in 2002. MUTYH is a component of
a base excision repair system that protects the genomic information from oxidative damage …

A 76-year-old white male with a history of adenocarcinoma of the rectosigmoideum and
multiple colonic polyps removed at the age of 38 and 39 years by an abdominoperitoneal …

MYH associated polyposis is a hereditary syndrome responsible for early colorectal cancer
with a distinct genetic pathway from the Familial Adenomatous Polyposis or the Hereditary …

Inherited biallelic mutations in the human MUTYH gene are responsible for the recessive
syndrome—adenomatous colorectal polyposis (MUTYH associated polyposis, MAP)—which …

MUTYH is a DNA glycosylase that excises adenine paired with 8-oxoguanine to prevent
mutagenesis in mammals. Biallelic germline mutations of MUTYH have been found in …

Monoallelic APC and biallelic MYH (homolog of Escherichia coli mutY) germ-line mutations
are independently associated with a strong predisposition to colorectal adenomas and …

Aim The aim was to determine the presentation, management and outcomes of MUTYH‐
associated polyposis (MAP). Method A prospectively maintained database was used to …

The MutY homolog (MYH) can excise adenines misincorporated opposite to guanines or 7,
8-dihydro-8-oxo-guanines (8-oxoG) during DNA replication; thereby preventing G: C to T: A …