Ginsenoside Rg1 Alleviates Ulcerative Colitis in Obese Mice by Regulating the Gut Microbiota–Lipid Metabolism–Th1/Th2/Th17 Cells Axis

Y Zhong, Q Xiao, J Huang, S Yu, L Chen… - Journal of Agricultural …, 2023 - ACS Publications
Ginsenoside Rg1 (G-Rg1) has various pharmacological properties including antiobesity,
immunomodulatory, and anti-inflammatory effects. This study aimed to explore the …

Impact of bariatric surgery on outcomes of patients with inflammatory bowel disease: a nationwide inpatient sample analysis, 2005–2018

IC Lin, H Liu - Obesity Surgery, 2024 - Springer
Purpose The global prevalence of inflammatory bowel disease (IBD) has steadily risen over
the past few decades. Bariatric surgery stands out as an effective strategy for inducing …

[HTML][HTML] Identifying inflammatory bowel disease patients at risk of metabolic dysfunction-associated fatty liver disease: usefulness of non-invasive steatosis predictive …

TL Capela, VM Silva, M Freitas, C Arieira… - BMC …, 2023 - Springer
Background Inflammatory bowel disease (IBD) patients have a higher risk of metabolic
dysfunction-associated fatty liver disease (MAFLD) compared with the general population …

The Rising Epidemic of Obesity in Patients with Inflammatory Bowel Disease

J Peraza, E Abbott, M Shneyderman… - … Treatment Options in …, 2024 - Springer
Abstract Purpose of Review This comprehensive review explores the increasing prevalence
of obesity among inflammatory bowel disease (IBD) patients and investigates its impact on …

Reviewing the impact of obesity on inflammatory bowel disease and considerations for optimizing management

W Ghusn, EV Loftus Jr, AM Johnson - Current Opinion in …, 2024 - journals.lww.com
The intersection of obesity and IBD presents a significant clinical challenge, with obesity
influencing the natural history of IBD and potentially affecting treatment efficacy. As obesity …

Electroacupuncture Reduces Inflammatory Bowel Disease in Obese Mice by Activating the Nrf2/HO-1 Signaling Pathways and Repairing the Intestinal Barrier

Y Yang, F Pang, M Zhou, X Guo, Y Yang… - Diabetes, Metabolic …, 2024 - Taylor & Francis
Background Electroacupuncture (EA) is used to treat inflammatory bowel disease (IBD).
Nevertheless, the precise mechanisms by which this approach safeguards against obesity …

[HTML][HTML] Adiponectin restores the obesity-induced impaired immunomodulatory function of mesenchymal stromal cells via glycolytic reprogramming

DV Pham, TK Nguyen, BL Nguyen, JO Kim… - … Pharmaceutica Sinica B, 2024 - Elsevier
Obesity has been known to negatively modulate the life-span and immunosuppressive
potential of mesenchymal stromal cells (MSC). However, it remains unclear what drives the …

[HTML][HTML] Human umbilical cord/placenta mesenchymal stem cell conditioned medium attenuates intestinal fibrosis in vivo and in vitro

YJ Choi, WR Kim, DH Kim, JH Kim, JH Yoo - Stem Cell Research & …, 2024 - Springer
Background A significant unmet need in inflammatory bowel disease is the lack of anti-
fibrotic agents targeting intestinal fibrosis. This study aimed to investigate the anti-fibrogenic …

[HTML][HTML] Computed tomography-based body composition parameters can predict short-term prognosis in ulcerative colitis patients

J Lu, H Xu, H Shi, J Zheng, T Cheng, M Zhou, X Han… - Insights into …, 2024 - Springer
Objectives Emerging evidence suggests a potential relationship between body composition
and short-term prognosis of ulcerative colitis (UC). Early and accurate assessment of rapid …

[HTML][HTML] Predictors of histologic remission in patients with biologic-naïve, moderate-to-severe ulcerative colitis treated with first-line biologic agents and small-molecule …

K Jo, KW Kim, HJ Lee, JP Im, JS Kim, SJ Koh - Intestinal Research, 2024 - irjournal.org
Methods We retrospectively analyzed the medical records of 92 patients who had been
diagnosed with UC and treated with first-line biologic agent treatment at our center, between …