Regulation of milk protein gene expression
JM Rosen, SL Wyszomierski… - Annual review of …, 1999 - annualreviews.org
▪ Abstract Studies using both transgenic mice and transfected mammary epithelial cells have
established that composite response elements containing multiple binding sites for several …
established that composite response elements containing multiple binding sites for several …
Production of pharmaceutical proteins from transgenic animals
LM Houdebine - Journal of biotechnology, 1994 - Elsevier
Different systems are being studied and used to prepare recombinant proteins for
pharmaceutical use. The blood, and still more the milk, from transgenic animals appear a …
pharmaceutical use. The blood, and still more the milk, from transgenic animals appear a …
Malnutrition in alcoholic and virus-related cirrhosis
L Caregaro, F Alberino, P Amodio, C Merkel… - The American journal of …, 1996 - Elsevier
The study aimed to define the prevalence, characteristics, and clinical importance of
nutritional disorders in patients with liver cirrhosis. Nutritional status was evaluated in 120 …
nutritional disorders in patients with liver cirrhosis. Nutritional status was evaluated in 120 …
Markedly increased susceptibility to natural sheep scrapie of transgenic mice expressing ovine prp
JL Vilotte, S Soulier, R Essalmani… - Journal of …, 2001 - Am Soc Microbiol
The susceptibility of sheep to scrapie is known to involve, as a major determinant, the nature
of the prion protein (PrP) allele, with the VRQ allele conferring the highest susceptibility to …
of the prion protein (PrP) allele, with the VRQ allele conferring the highest susceptibility to …
Transgenic dairy cattle: genetic engineering on a large scale
RJ Wall, DE Kerr, KR Bondioli - Journal of Dairy Science, 1997 - Elsevier
Amid the explosion of fundamental knowledge generated from transgenic animal models, a
small group of scientists has been producing transgenic livestock with goals of improving …
small group of scientists has been producing transgenic livestock with goals of improving …
[HTML][HTML] Structure and function of milk protein genes
JC Mercier, JL Vilotte - Journal of dairy science, 1993 - Elsevier
Interspecies comparisons of cDNA and mosaic milk protein genes have confirmed their high
rate of evolution, but the overall gene organization has been conserved. The three Ca …
rate of evolution, but the overall gene organization has been conserved. The three Ca …
Preeclampsia-like symptoms induced in mice by fetoplacental expression of STOX1 are reversed by aspirin treatment
L Doridot, B Passet, C Méhats, V Rigourd… - …, 2013 - Am Heart Assoc
Preeclampsia (PE) is a common human-specific pregnancy disorder defined by
hypertension and proteinuria during gestation and responsible for maternal and fetal …
hypertension and proteinuria during gestation and responsible for maternal and fetal …
Transgenesis in rats: technical aspects and models
B Charreau, L Tesson, JP Soulillou, C Pourcel… - Transgenic …, 1996 - Springer
The production of transgenic rats by DNA-microinjection into fertilizer ova has now become
an established procedure, although fewer than 20 lines have been described during the last …
an established procedure, although fewer than 20 lines have been described during the last …
Creation and phenotypic analysis of alpha-lactalbumin-deficient mice.
MG Stinnakre, JL Vilotte, S Soulier… - Proceedings of the …, 1994 - National Acad Sciences
alpha-Lactalbumin is an abundant milk-specific calcium metalloprotein which has an
evolutionary relationship to lysozyme. It modifies the substrate specificity of a Golgi …
evolutionary relationship to lysozyme. It modifies the substrate specificity of a Golgi …
High-level synthesis of a heterologous milk protein in the mammary glands of transgenic swine.
RJ Wall, VG Pursel, A Shamay… - Proceedings of the …, 1991 - National Acad Sciences
The whey acidic protein (WAP) is a major milk protein in mice, rats, and rabbits but has not
been found in milk of livestock including swine. To determine whether mammary gland …
been found in milk of livestock including swine. To determine whether mammary gland …