Multiple endocrine neoplasia type 1 and the pancreas: diagnosis and treatment of functioning and non-functioning pancreatic and duodenal neuroendocrine …

B Niederle, A Selberherr, DK Bartsch, ML Brandi… - …, 2021 - karger.com
The better understanding of the biological behavior of multiple endocrine neoplasia type 1
(MEN1) organ manifestations and the increase in clinical experience warrant a revision of …

Inherited pancreatic endocrine tumor syndromes: advances in molecular pathogenesis, diagnosis, management, and controversies

RT Jensen, MJ Berna, DB Bingham, JA Norton - Cancer, 2008 - Wiley Online Library
Pancreatic endocrine tumors (PETs) have long fascinated clini-cians, because some can
release biologically active hormones that cause distinct syndromes and provide important …

Causes of death and prognostic factors in multiple endocrine neoplasia type 1: a prospective study: comparison of 106 MEN1/Zollinger-Ellison syndrome patients with …

T Ito, H Igarashi, H Uehara, MJ Berna, RT Jensen - Medicine, 2013 - journals.lww.com
Multiple endocrine neoplasia type 1 (MEN1) is classically characterized by the development
of functional or nonfunctional hyperplasia or tumors in endocrine tissues (parathyroid …

Surgery to cure the Zollinger–Ellison syndrome

JA Norton, DL Fraker, HR Alexander… - … England Journal of …, 1999 - Mass Medical Soc
Background and Methods The role of surgery in patients with the Zollinger–Ellison
syndrome is controversial. To determine the efficacy of surgery in patients with this …

Multiple endocrine neoplasia type 1 and Zollinger-Ellison syndrome: a prospective study of 107 cases and comparison with 1009 cases from the literature

F Gibril, M Schumann, A Pace, RT Jensen - Medicine, 2004 - journals.lww.com
In patients with multiple endocrine neoplasia type 1 (MEN1), the most common functional
pancreatic endocrine tumor (PET) syndrome is Zollinger-Ellison syndrome (ZES). ZES has …

Neuroendocrine tumor disease: an evolving landscape

A Frilling, G Åkerström, M Falconi… - Endocrine-related …, 2012 - erc.bioscientifica.com
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) represent a heterogenous
group of tumors arising from a variety of neuroendocrine cell types. The incidence and …

Epidemiology data on 108 MEN 1 patients from the GTE with isolated nonfunctioning tumors of the pancreas

F Triponez, D Dosseh, P Goudet, P Cougard… - Annals of …, 2006 - journals.lww.com
Objective: To analyze the penetrance and clinical course of isolated nonfunctioning tumors
of the pancreas (NFTP) in MEN 1 patients, and to propose a strategy for managing them …

Duodenal neuroendocrine tumors: classification, functional syndromes, diagnosis and medical treatment

KM Hoffmann, M Furukawa, RT Jensen - Best practice & research Clinical …, 2005 - Elsevier
Duodenal neuroendocrine tumors (NETs) comprise 2–3% of all GI endocrine tumors and are
increasing in frequency. These include gastrinomas, somatostatinomas, nonfunctional …

Serum gastrin in Zollinger-Ellison syndrome: I. Prospective study of fasting serum gastrin in 309 patients from the National Institutes of Health and comparison with …

MJ Berna, KM Hoffmann, J Serrano, F Gibril… - Medicine, 2006 - journals.lww.com
The assessment of fasting serum gastrin (FSG) is essential for the diagnosis and
management of patients with the Zollinger-Ellison syndrome (ZES). Although many studies …

Resolved and unresolved controversies in the surgical management of patients with Zollinger-Ellison syndrome

JA Norton, RT Jensen - Annals of surgery, 2004 - journals.lww.com
Objective: Highlight unresolved controversies in the management of Zollinger-Ellison
syndrome (ZES). Summary Background Data: Recent studies have resolved some of the …