Protein coding genes are transcribed by Polymerase II, under the control of short discrete
DNA elements in promoters and enhancers, recognized with high efficiency and specificity …

Carbon Catabolite Repression (CCR) has fascinated scientists and researchers around the
globe for the past few decades. This important mechanism allows preferential utilization of …

Ki-67 serves as a prominent cancer marker. We describe how expression of the MKI67 gene
coding for Ki-67 is controlled during the cell cycle. MKI67 mRNA and Ki-67 protein are …

When unfolded proteins accumulate in the endoplasmic reticulum (ER), transcription of
glucose-regulated proteins (GRPs) representing ER-resident molecular chaperones is …

The CCAAT box is one of the most common cis-elements present in eukaryotic promoters
and is bound by the transcription factor NUCLEAR FACTOR Y (NF-Y). NF-Y is composed of …

Plant cell wall consists mainly of the large biopolymers cellulose, hemicellulose, lignin and
pectin. These biopolymers are degraded by many microorganisms, in particular filamentous …

Fungi play a major role in the global carbon cycle because of their ability to utilize plant
biomass (polysaccharides, proteins, and lignin) as carbon source. Due to the complexity and …

Transcription factors belonging to the CCAAT-box binding factor family (also known as the
Nuclear Factor Y) are present in all higher eukaryotes. Studies in plants have revealed that …

Research on regulation of cellulases and hemicellulases gene expression may be very
useful for increasing the production of these enzymes in their native producers. Mechanisms …

Suberoylanilide hydroxamic acid (SAHA) is a potent inhibitor of histone deacetylases
(HDACs) that causes growth arrest, differentiation, and/or apoptosis of many tumor types in …