Anti-depressant properties of crocin molecules in saffron

SA Siddiqui, A Ali Redha, ER Snoeck, S Singh… - Molecules, 2022 - mdpi.com
Saffron is a valued herb, obtained from the stigmas of the C. sativus Linn (Iridaceae), with
therapeutic effects. It has been described in pharmacopoeias to be variously acting …

Moroccan medicinal plants traditionally used for the treatment of skin diseases: From ethnobotany to clinical trials

M Ajjoun, L Kharchoufa, IA Merrouni… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Skin diseases are among the most common human health
affections. A healthy skin promotes a healthy body that can be achieved through modern …

Depression and its phytopharmacotherapy—a narrative review

L Dobrek, K Głowacka - International Journal of Molecular Sciences, 2023 - mdpi.com
Depression is a mental health disorder that develops as a result of complex psycho-neuro-
immuno-endocrinological disturbances. This disease presents with mood disturbances …

Natural products inhibitors of monoamine oxidases—Potential new drug leads for neuroprotection, neurological disorders, and neuroblastoma

ND Chaurasiya, F Leon, I Muhammad, BL Tekwani - Molecules, 2022 - mdpi.com
Monoamine oxidase inhibitors (MAOIs) are an important class of drugs prescribed for
treatment of depression and other neurological disorders. Evidence has suggested that …

Novel pharmacological approaches to the treatment of depression

E Elias, AY Zhang, MT Manners - Life, 2022 - mdpi.com
Major depressive disorder is one of the most prevalent mental health disorders. Monoamine-
based antidepressants were the first drugs developed to treat major depressive disorder …

Bioactive Components and Biological Activities of Crocus sativus L. Byproducts: A Comprehensive Review

Y Wu, Y Gong, J Sun, Y Zhang, Z Luo… - Journal of Agricultural …, 2023 - ACS Publications
The production of saffron spice results in numerous byproducts, as only 15 g of spice can be
produced from 1 kg of flowers, indicating that over 90% of the saffron flower material is …

Thymoquinone-enriched naringenin-loaded nanostructured lipid carrier for brain delivery via nasal route: in vitro prospect and in vivo therapeutic efficacy for the …

FF Qizilbash, MU Ashhar, A Zafar, Z Qamar, Annu, J Ali… - Pharmaceutics, 2022 - mdpi.com
In the current research, a thymoquinone-enriched naringenin (NGN)-loaded nanostructured
lipid carrier (NLC) was developed and delivered via the nasal route for depression …

A recent review on bio-availability enhancement of poorly water-soluble drugs by using bioenhancer and nanoparticulate drug delivery system

M Kumar, D Kumar, S Kumar, A Kumar… - Current …, 2022 - ingentaconnect.com
Background: Intravenous route of drug administration has maximum bioavailability, which
shows 100% of the drug reaches blood circulation, whereas the oral administration of drugs …

[HTML][HTML] Flower, stem, and leaf extracts from Hypericum perforatum L. to synthesize gold nanoparticles: Effectiveness and antioxidant activity

R Rey-Méndez, MC Rodríguez-Argüelles… - Surfaces and …, 2022 - Elsevier
The significance of gold nanoparticles in nanobiotechnology and the trend towards the
development of green methods of synthesis has boosted research on the use of new natural …

[HTML][HTML] Applications of the One Health concept: Current status in the Middle East

ALE Laith, S Sendyani, M Alnemri - Journal of Biosafety and Biosecurity, 2023 - Elsevier
Abstract Background The One Health concept (OHC) seeks to improve the health of plants,
animals, and humans because improving animal and plant health will increase the capacity …