Biosynthesis of fungal melanins and their importance for human pathogenic fungi

K Langfelder, M Streibel, B Jahn, G Haase… - Fungal genetics and …, 2003 - Elsevier
For more than 40 years fungi have been known to produce pigments known as melanins.
Predominantly these have been dihydroxyphenylalanine (DOPA)-melanin and …

Aspergillus fumigatus: Principles of Pathogenesis and Host Defense

TM Hohl, M Feldmesser - Eukaryotic cell, 2007 - Am Soc Microbiol
Aspergillus fumigatus is a ubiquitous saprophytic mold (67) that forms airborne spores
(conidia). Humans inhale, on average, hundreds of these infectious propagules daily. In …

[PDF][PDF] Genes and molecules involved in Aspergillus fumigatus virulence

A Rementeria, N López-Molina, A Ludwig… - Rev Iberoam …, 2005 - reviberoammicol.com
Aspergillus fumigatus causes a wide range of diseases that include mycotoxicosis, allergic
reactions and systemic diseases (invasive aspergillosis) with high mortality rates …

Aspergillus fumigatus: Growth and virulence

JC Rhodes - Medical mycology, 2006 - Taylor & Francis
Aspergillus fumigatus is a ubiquitous fungus that plays an important role in carbon and
nitrogen recycling in nature. Because A. fumigatus is thermotolerant, it is a predominant …

[PDF][PDF] Ecology and taxonomy of pathogenic aspergilli

HC Gugnani - Front Biosci, 2003 - academia.edu
Historical Perspective 3. Introduction to Aspergillus 4. Importance of Aspergilli in Industry,
Agriculture, and Human Health 4.1. Industrial importance of aspergilli 4.2. Role of aspergilli …

cAMP signaling in Aspergillus fumigatus is involved in the regulation of the virulence gene pksP and in defense against killing by macrophages

B Liebmann, S Gattung, B Jahn… - Molecular Genetics and …, 2003 - Springer
Aspergillus fumigatus is an important pathogen of immunocompromised hosts, causing
pneumonia and invasive disseminated disease and resulting in high mortality. In order to …

Deletion of the Regulatory Subunit of Protein Kinase A in Aspergillus fumigatus Alters Morphology, Sensitivity to Oxidative Damage, andVirulence

W Zhao, JC Panepinto, JR Fortwendel, L Fox… - Infection and …, 2006 - Am Soc Microbiol
Aspergillus fumigatus is an important opportunistic fungal pathogen. The cAMP-dependent
protein kinase (PKA) signaling pathway plays an important role in regulating morphology …

Deletion of the Aspergillus fumigatus Gene Encoding the Ras-Related Protein RhbA Reduces Virulence in a Model of Invasive Pulmonary Aspergillosis

JC Panepinto, BG Oliver, JR Fortwendel… - Infection and …, 2003 - Am Soc Microbiol
Aspergillus fumigatus is the predominant mold pathogen in patients who lack functional
innate immunity. The A. fumigatus rhbA gene was first identified as a transcript that was …

Divergent Protein Kinase A isoforms co‐ordinately regulate conidial germination, carbohydrate metabolism and virulence in Aspergillus fumigatus

KK Fuller, DL Richie, X Feng, K Krishnan… - Molecular …, 2011 - Wiley Online Library
The genome of Aspergillus fumigatus encodes two isoforms of the catalytic subunit of the
cAMP‐dependent Protein Kinase (PKA). Although deletion of the class I isoform, pkaC1 …

Interaction of pathogenic fungi with host cells: Molecular and cellular approaches

MJS Mendes-Giannini, CP Soares… - FEMS Immunology & …, 2005 - academic.oup.com
This review provides an overview of several molecular and cellular approaches that are
likely to supply insights into the host-fungus interaction. Fungi present intra-and/or …