[PDF][PDF] Extracellular vesicles produced by bone marrow mesenchymal stem cells attenuate renal fibrosis, in part by inhibiting the RhoA/ROCK pathway, in a UUO rat …

Z Shi, Q Wang, Y Zhang, D Jiang - scholar.archive.org
Background: Renal interstitial fibrosis is a critical symptom of chronic kidney disease that is
associated with high incidence. Extracellular vesicles produced by bone marrow …

30N 1900E, RM 4R214 14

S Xie, J Su, A Lu, Y Lai, S Mo, M Pu, T Yang - journals.physiology.org
Tubulointerstitial fibrosis has been regarded as a critical event in the pathogenesis of 20
chronic kidney disease (CKD). Soluble form of PRR (sPRR), generated by site-1 protease …

[PDF][PDF] Inhibition of histone readers bromodomain extra-terminal proteins alleviates scleroderma fibrosis

S Vichaikul, PJ Palisoc, M Ali, PL Campbell, MA Amin… - researchgate.net
Inhibition of histone readers bromodomain extra-terminal proteins alleviates scleroderma
fibrosis Sirapa Vichaikul1, Pamela J. P Page 1 1 Inhibition of histone readers bromodomain …

[图书][B] Pharmacologic PTEN Upregulation: A Novel Approach to Maintain Smooth Muscle Cell Homeostasis Following Vascular Injury

KA Strand - 2020 - search.proquest.com
The primary aim of this thesis work was to identify compounds that upregulate phosphatase
and tensin homolog (PTEN) expression in smooth muscle cells (SMCs), with the expectation …

[PDF][PDF] JOURNALOFNEPHROLOGYAD VANCES

SX Ma, YQ Shang, HQ Zhang, W Su - oap-onlinejournals.org
Renal fibrosis was a chronic and progressive process affecting kidneys in chronic kidney
disease (CKD), regardless of cause. Although no effective targeted therapy yet existed to …

Epigenética en la enfermedad renal: Investigación de las proteínas BET como potenciales dianas terapéuticas

JLM Pascual - 2018 - dialnet.unirioja.es
La enfermedad renal crónica (ERC) es un problema de salud muy relevante a nivel
mundial, que desemboca en enfermedad renal terminal o muerte por eventos …

[PDF][PDF] Investigating BET Proteins as a Therapeutic Target in Keloid Scarring

RE Bell - 2018 - kclpure.kcl.ac.uk
Keloid scars form due to an over-exuberant, fibrotic wound response in the skin of
predisposed individuals. There is currently no clear genetic link identified, and limited …

[PDF][PDF] microglial inflammation via MAPK/NFκB signaling

H Wang, W Huang, M Liang, Y Shi, C Zhang… - 2018 - cellandbioscience.biomedcentral …
Background: Microglia activation is a crucial event in neurodegenerative disease. The
depression of microglial inflammatory response is considered a promising therapeutic …

[引用][C] Myelofibrosis: In search for BETter targeted therapies

GA Palumbo, A Duminuco - Journal of Clinical Oncology, 2023 - ascopubs.org
Mutations in the JAK-STAT pathway are pathognomonic of BCR-ABL1–negative
myeloproliferative neoplasms (MPNs) 1 including myelofibrosis (MF). JAK-STAT pathway …

[引用][C] BET 蛋白抑制剂JQ1 对MRL/lpr 狼疮小鼠外周B 细胞分化的影响

曾珊, 肖游君, 邱茜, 李昊, 徐思琪, 王竞男, 石茂华… - 中国免疫学杂志