Tissue factor, blood coagulation, and beyond: an overview

AJ Chu - International journal of inflammation, 2011 - Wiley Online Library
Emerging evidence shows a broad spectrum of biological functions of tissue factor (TF). TF
classical role in initiating the extrinsic blood coagulation and its direct thrombotic action in …

Circulating tissue factor‐positive extracellular vesicles and their association with thrombosis in different diseases

Y Hisada, ATA Sachetto, N Mackman - Immunological Reviews, 2022 - Wiley Online Library
Tissue factor (TF) is a procoagulant protein released from activated host cells, such as
monocytes, and tumor cells on extracellular vesicles (EVs). TF+ EVs are observed in the …

Interconnections between autophagy and the coagulation cascade in hepatocellular carcinoma

KD Chen, CC Wang, MC Tsai, CH Wu, HJ Yang… - Cell death & …, 2014 - nature.com
Autophagy has an important role in tumor biology of hepatocellular carcinoma (HCC).
Recent studies demonstrated that tissue factor (TF) combined with coagulation factor VII …

Reduced platelet activation and platelet aggregation in patients with alcoholic liver cirrhosis

PJ Vinholt, AM Hvas, C Nielsen, AC Söderström… - Platelets, 2018 - Taylor & Francis
Results from previous studies regarding platelet function in liver cirrhosis are discordant.
The aim was to investigate platelet activation and platelet aggregation in patients with …

Hepatocyte tissue factor contributes to the hypercoagulable state in a mouse model of chronic liver injury

PE Rautou, K Tatsumi, S Antoniak, AP Owens III… - Journal of …, 2016 - Elsevier
Background & Aims Patients with chronic liver disease and cirrhosis have a dysregulated
coagulation system and are prone to thrombosis. The basis for this hypercoagulable state is …

Monocyte-platelet aggregates and platelet micro-particles in patients with post-hepatitic liver cirrhosis

D Sayed, NF Amin, GM Galal - Thrombosis research, 2010 - Elsevier
INTRODUCTION: Monocytes are the cells that play a crucial role in the pathogenesis of liver
damage and liver cirrhosis (LC), and as platelets, by connecting hemostasis and …

Selective internal radiotherapy changes the immune profiles of extracellular vesicles and their immune origin in patients with inoperable cholangiocarcinoma

F Haag, A Manikkam, D Kraft, C Bär, V Wilke… - Cells, 2022 - mdpi.com
The incidence of cholangiocellular carcinoma (CCA) is rising worldwide. As there are no
specific early symptoms or specific markers of CCA, it is often diagnosed in later inoperable …

[HTML][HTML] Establishment and verification of a prognostic model based on coagulation and fibrinolysis-related genes in hepatocellular carcinoma

M Fan, L Lu, H Shang, Y Lu, Y Yang, X Wang… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Background: Studies have shown that coagulation and fibrinolysis (CFR) are correlated with
Hepatocellular carcinoma (HCC) progression and prognosis. We aim to build a model …

[PDF][PDF] Геморрагический синдром при циррозе печени

ИА Куркина, ОС Волкова, МВ Маевская… - Рос. журн …, 2012 - old-gastro-j.ru
Основные положения. Физиология системы гемостаза тесно связана с функцией
печени, потому что паренхиматозные клетки вырабатывают большинство факторов …

Intrahepatic metastases may be specific to hepatocellular carcinoma due to the coagulation and fibrinolytic systems

X Li, B Gu, B Wang, Z Feng, Y Ma, H Li… - Oncology …, 2020 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is different from other solid tumors because it is commonly
associated with the occurrence of intrahepatic metastasis. Additionally, the liver, unlike other …