Astragalus membranaceus: A Review of Its Antitumor Effects on Non-Small Cell Lung Cancer

Z Li, J Liu, H Cui, W Qi, Y Tong… - Cancer Management and …, 2024 - Taylor & Francis
The rising global morbidity and mortality rates of non-small cell lung cancer (NSCLC)
underscore the urgent need for more effective treatments. Current therapeutic modalities …

Arsenic trioxide augments immunogenic cell death and induces cGAS-STING-IFN pathway activation in hepatocellular carcinoma

X Li, YF Pan, YB Chen, QQ Wan, YK Lin… - Cell Death & …, 2024 - nature.com
The treatment of hepatocellular carcinoma (HCC) is particularly challenging due to the
inherent tumoral heterogeneity and easy resistance towards chemotherapy and …

[HTML][HTML] OLFM4 promotes the progression of intestinal metaplasia through activation of the MYH9/GSK3β/β-catenin pathway

H Wei, W Li, L Zeng, N Ding, K Li… - Molecular …, 2024 - molecular-cancer.biomedcentral …
Intestinal metaplasia (IM) is classified into complete intestinal metaplasia (CIM) and
incomplete intestinal metaplasia (IIM). Patients diagnosed with IIM face an elevated …

[HTML][HTML] Neutrophil extracellular traps promote immune escape in hepatocellular carcinoma by up-regulating CD73 through Notch2

Y Yu, C Zhang, B Dong, Z Zhang, X Li, S Huang… - Cancer Letters, 2024 - Elsevier
Immune escape is the main reason that immunotherapy is ineffective in hepatocellular
carcinoma (HCC). Here, this study illustrates a pathway mediated by neutrophil extracellular …

Jozimine A2, a Dimeric Naphthylisoquinoline (NIQ) Alkaloid, Shows In Vitro Cytotoxic Effects against Leukemia Cells through NF-κB Inhibition

R Damiescu, R Yücer, SM Klauck… - International Journal of …, 2024 - mdpi.com
Naphthylisoquinoline (NIQ) alkaloids are rising as a promising class of secondary
metabolites with pharmaceutical potential. NF-κB has already been recognized as a …

Therapeutic Opportunities in Cutaneous T-cell Lymphoma

S Valero-Diaz, C Amato, B Casar - 2024 - preprints.org
Cutaneous T-cell lymphomas (CTCLs) are a heterogeneous group of T-cell lymphomas
characterised by high relapse rates and no curative treatments unless the allogeneic stem …