Investigation of crystal structures, spectral (FT-IR and NMR) analysis, DFT, and molecular docking studies of novel piperazine derivatives as antineurotic drugs
E Jaziri, H Louis, C Gharbi, F Lefebvre… - Journal of Molecular …, 2023 - Elsevier
In this article, the psychopharmacological potential of piperazine derivatives as an
antineurotic agent was presented. Crystal and molecular structure of newly synthesized …
antineurotic agent was presented. Crystal and molecular structure of newly synthesized …
Design, synthesis of 1, 2, 4-triazine derivatives as antidepressant and antioxidant agents: In vitro, in vivo and in silico studies
The novel series of substituted-N-(5, 6-diphenyl-1, 2, 4-triazin-3-yl) benzamides (R: 1–12)
were designed, synthesized and evaluated for in-vitro and in-vivo antidepressant-like …
were designed, synthesized and evaluated for in-vitro and in-vivo antidepressant-like …
Functional consequences of a rare human serotonergic 5-HT1A receptor variant
M Tauber, Y Ben-Chaim - Frontiers in Pharmacology, 2023 - frontiersin.org
Serotonin (5-HT) plays a central role in various brain functions via the activation of a family
of receptors, most of them G protein coupled receptors (GPCRs). 5-HT1A receptor, the most …
of receptors, most of them G protein coupled receptors (GPCRs). 5-HT1A receptor, the most …
Synthesis and biological evaluation of (+)-paeoveitol derivatives as novel antidepressants
The antidepressant activity of (+) and (−)-paeoveitol was first evaluated using the forced
swimming test (FST), and (+)-paeoveitol showed potential antidepressant activity by …
swimming test (FST), and (+)-paeoveitol showed potential antidepressant activity by …