Thiazole-containing compounds as therapeutic targets for cancer therapy

PC Sharma, KK Bansal, A Sharma, D Sharma… - European journal of …, 2020 - Elsevier
In the last few decades, considerable progress has been made in anticancer agents
development, and several new anticancer agents of natural and synthetic origin have been …

Anticancer potential of thiazole derivatives: a retrospective review

S Jain, S Pattnaik, K Pathak, S Kumar… - Mini reviews in …, 2018 - ingentaconnect.com
This review brings forth the potential of thiazole derivatives for their anticancer activities. The
emphasis is placed on the structural diversity of thiazole derivatives, responsible for their …

[HTML][HTML] Thiazole ring-the antimicrobial, anti-inflammatory, and anticancer active scaffold

S Hosseininezhad, A Ramazani - Arabian Journal of Chemistry, 2023 - Elsevier
Background Thiazole ring is one of the most important heterocycle scaffolds in organic and
medicinal chemistry due to this scaffold being the backbone of numerous drugs and their …

Synthesis of 2-trifluoromethyl thiazoles via [3+ 2] cycloaddition of pyridinium 1, 4-zwitterionic thiolates with CF 3 CN

Y Yao, B Lin, M Wu, Y Zhang, Y Huang… - Organic & …, 2022 - pubs.rsc.org
2, 2, 2-Trifluoroacetaldehyde O-(aryl) oxime was employed for the [3+ 2] cycloaddition of
pyridinium 1, 4-zwitterionic thiolates for the synthesis of 2-trifluoromethyl 4, 5-disubstituted …

Antibacterial evaluation and molecular docking studies of pyrazole–thiosemicarbazones and their pyrazole–thiazolidinone conjugates

O Ebenezer, A Singh-Pillay, NA Koorbanally… - Molecular Diversity, 2021 - Springer
A library of pyrazole–thiazolidinone conjugates was synthesized using a molecular
hybridization approach through a Vilsmeier–Haack reaction. The compounds were tested for …

[HTML][HTML] A potential antifungal agent: Insight into the antifungal mechanism against Phomopsis sp

C Yuan, T Zhang, J Tian, T Deng, H Xin, Y Liu… - Arabian Journal of …, 2024 - Elsevier
Abstract 19 myricetin derivatives containing thiazole were designed and synthesized. Their
fungicidal activities in vitro against ten species of plant pathogenic fungi were evaluated …

2, 4, 5-trisubstituted thiazole: A privileged scaffold in drug design and activity improvement

Z Zhang, B Shu, Y Zhang, GS Deora… - Current Topics in …, 2020 - ingentaconnect.com
Thiazole is an important 5-membered heterocyclic compound containing nitrogen and sulfur
atoms with various pharmaceutical applications including anti-inflammatory, anti-cancer, anti …

The effect of newly synthesized progesterone derivatives on apoptotic and angiogenic pathway in MCF-7 breast cancer cells

SMM Yahya, AO Abdelhamid, MM Abd-Elhalim… - Steroids, 2017 - Elsevier
Due to its high potency and selectivity, anticancer agents consisting of combined molecules
have gained great interests. The current study introduces newly synthesized progesterone …

New thiazoline-tetralin derivatives and biological activity evaluation

G Turan-Zitouni, L Yurttaş, A Tabbi, G Akalın Çiftçi… - Molecules, 2018 - mdpi.com
In this study, novel N′-(3-cyclohexyl/phenyl-4-(substituted phenyl) thiazole-2 (3 H)-ylidene)-
2-[(5, 6, 7, 8-tetrahydronaphthalen-2-yl) oxy] acetohydrazide (4a–4k) derivatives were …

Synthesis, spectral properties and anticancer studies of novel hetrocyclic azo dye ligand derived from 2-amino-5-methyl thiazole with some transition metal complexes

KJ Al-Adilee, HM Hessoon - Journal of Physics: Conference …, 2019 - iopscience.iop.org
This research included preparation of the thiazolyl azo ligand 2-[2--(5-Methyl thiazolyl) azo]-
4-Ethoxy phenol (MeTAEP) and their metal complexes which was prepared by coupling of …