Introduction A major consideration for the implementation of a learning health system (LHS)
is consent from participants to the use of their data for research purposes. The main …

Background Robust technology infrastructure is needed to enable learning health care
systems to improve quality, access, and cost. Such infrastructure relies on the trust and …

A survey was conducted to assess citizens, research ethics committee members, and
researchers' attitude toward information and consent for the secondary use of health data for …

Background: For pragmatic clinical research comparing commonly used treatments,
questions exist about if and how to notify participants about it and secure their authorization …

Cluster randomised clinical trials present unique challenges in meeting ethical obligations to
those who are treated at a randomised site. Obtaining informed consent for research within …

An important institutional and societal dilemma is how to notify people when they are not
meeting performance standards, such as in placing people on a probationary status at …

Conducting research in usual care settings—which includes pragmatic clinical trials,
comparative effectiveness research, and analyses of clinical databases—is associated with …