Molecular mechanisms and therapeutic perspectives of peroxisome proliferator‐activated receptor α agonists in cardiovascular health and disease

Y Pu, CK Cheng, H Zhang, JY Luo… - Medicinal Research …, 2023 - Wiley Online Library
The prevalence of cardiovascular disease (CVD) has been rising due to sedentary lifestyles
and unhealthy dietary patterns. Peroxisome proliferator‐activated receptor α (PPARα) is a …

[HTML][HTML] On the application of 3d metals for C–H activation toward bioactive compounds: The key step for the synthesis of silver bullets

RL Carvalho, AS de Miranda… - Beilstein Journal of …, 2021 - beilstein-journals.org
Several valuable biologically active molecules can be obtained through C–H activation
processes. However, the use of expensive and not readily accessible catalysts complicates …

[HTML][HTML] Propionate alleviates myocardial ischemia-reperfusion injury aggravated by angiotensin II dependent on caveolin-1/ACE2 axis through GPR41

F Deng, LQ Zhang, H Wu, Y Chen, WQ Yu… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Myocardial ischemia/reperfusion (I/R) injury is still a lack of effective therapeutic drugs, and
its molecular mechanism is urgently needed. Studies have shown that the intestinal flora …

Acupuncture at Neiguan suppresses PVCs occurring post-myocardial infarction by alleviating inflammation and fibrosis

H Hong, X Cao, T Deng, XM Meng, YM Li, LJ Zhu, J Lv… - Chinese medicine, 2022 - Springer
Abstract Background Acupuncture at Neiguan (PC6) has long been used for treating
cardiovascular diseases, but its antiarrhythmic effect and the underlying mechanisms have …

Identification of co-expressed central genes and transcription factors in acute myocardial infarction and diabetic nephropathy

B Li, X Zhao, W Xie, Z Hong, Y Cao, Y Zhang… - BMC Medical …, 2024 - Springer
Background Acute myocardial infarction (AMI) and diabetic nephropathy (DN) are common
clinical co-morbidities, but they are challenging to manage and have poor prognoses. There …