The chirality of small metabolic molecules is important in controlling physiological processes
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …

Substantial amounts of d-amino acids are present in mammalian tissues; their function,
origin and relationship between pathophysiological processes have been of great interest …

This paper reviews and interprets a method for determining the nutritional value of d-amino
acids, d-peptides, and amino acid derivatives using a growth assay in mice fed a synthetic …

The enantiomers of chiral amino acids play versatile roles in biological systems including
humans. They are also very useful in the asymmetric synthesis of diverse chiral organic …

The concentrations of several d-amino acids have been reported to significantly increase in
the plasma of patients with chronic kidney disease (CKD). However, the amounts of these d …

D-Amino acids, long-term undetected enantiomers of L-amino acids, are now emerging as
potential biomarkers, especially for kidney diseases. Management of chronic kidney disease …

An automated two-dimensional HPLC-MS/MS system was designed and developed for the
highly selective determination of trace levels of d-amino acids. As the targets, frequently …

The incidence of dementia, a clinical symptom characterized by severe cognitive decline, is
increasing worldwide. Predictive biomarkers are therefore required for early identification …

Chiral separations using gas chromatography (GC) are mainly performed on chiral
stationary phases (CSPs) capable of hydrogen bonding, coordination and inclusion, such as …

Chiral molecules are stereoselective with regard to specific biological functions.
Enantiomers differ considerably in their physiological reactions with the human body …