Fundamentals of redox regulation in biology

H Sies, RJ Mailloux, U Jakob - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Oxidation–reduction (redox) reactions are central to the existence of life. Reactive species of
oxygen, nitrogen and sulfur mediate redox control of a wide range of essential cellular …

[HTML][HTML] Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nanomaterials with multiple enzyme-mimicking activities, and low …

K Jomova, SY Alomar, SH Alwasel, E Nepovimova… - Archives of …, 2024 - Springer
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are well recognized for
playing a dual role, since they can be either deleterious or beneficial to biological systems …

[HTML][HTML] Food polyphenols as preventive medicine

J Kanner - Antioxidants, 2023 - mdpi.com
Reactive oxygen species (ROS) are the initiators in foods and in the stomach of oxidized
dietary lipids, proteins, and lipid-oxidation end-products (ALEs), inducing in humans the …

[HTML][HTML] Disposable facemask waste combustion emits neuroactive smoke particulate matter

A Pastukhov, K Paliienko, N Pozdnyakova… - Scientific Reports, 2023 - nature.com
Tremendous deposits of disposable medical facemask waste after the COVID-19 pandemic
require improvement of waste management practice according to WHO report 2022 …

[HTML][HTML] Are age-related neurodegenerative diseases caused by a lack of the diet-derived compound ergothioneine?

B Halliwell, I Cheah - Free Radical Biology and Medicine, 2024 - Elsevier
We propose that the diet-derived compound ergothioneine (ET) is an important nutrient in
the human body, especially for maintenance of normal brain function, and that low body ET …

[HTML][HTML] Mitochondrial glutathione in cellular redox homeostasis and disease manifestation

TH Chen, HC Wang, CJ Chang, SY Lee - International Journal of …, 2024 - mdpi.com
Mitochondria are critical for providing energy to maintain cell viability. Oxidative
phosphorylation involves the transfer of electrons from energy substrates to oxygen to …

[HTML][HTML] Bioactive compounds from nature: Antioxidants targeting cellular transformation in response to epigenetic perturbations induced by oxidative stress

A Bouyahya, S Bakrim, S Aboulaghras… - Biomedicine & …, 2024 - Elsevier
Oxidative stress results from a persistent imbalance in oxidation levels that promotes
oxidants, playing a crucial role in the early and sustained phases of DNA damage and …

Iron and atherosclerosis: Lessons learned from rabbits relevant to human disease

B Halliwell, F Watt, R Minqin - Free Radical Biology and Medicine, 2023 - Elsevier
The role of iron in promoting atherosclerosis, and hence the cardiovascular,
neurodegenerative and other diseases that result from atherosclerosis, has been fiercely …

[HTML][HTML] Reassessing the role of phytochemicals in cancer chemoprevention

GL Russo, C Spagnuolo, M Russo - Biochemical Pharmacology, 2024 - Elsevier
In this comprehensive review we tried to reassess the role of phytochemicals in cancer
chemoprevention. The exploration of the “synergistic effect” concept, advocating combined …

[HTML][HTML] 50 shades of oxidative stress: A state-specific cysteine redox pattern hypothesis

JN Cobley - Redox Biology, 2023 - Elsevier
Oxidative stress is biochemically complex. Like primary colours, specific reactive oxygen
species (ROS) and antioxidant inputs can be mixed to create unique “shades” of oxidative …