Executive summary Tuberculosis can be treated, prevented, and cured. Rapid, sustained
declines in tuberculosis deaths in many countries during the past 50 years provide …

SUMMARY A syndemic is defined as the convergence of two or more diseases that act
synergistically to magnify the burden of disease. The intersection and syndemic interaction …

Of the 33.2 million persons infected with human immunodeficiency virus (HIV), one-third are
estimated to also be infected with Mycobacterium tuberculosis. In 2008, there were an …

Rapid progress has been made in the development of new diagnostic assays for
tuberculosis in recent years. New technologies have been developed and assessed, and …

Background The World Health Organization recommends the screening of all people living
with HIV for tuberculosis (TB) disease, followed by TB treatment, or isoniazid preventive …

Human infection with Mycobacterium tuberculosis can progress to active disease, be
contained as latent infection, or be eradicated by the host response. Tuberculosis …

Background The World Health Organization has endorsed the Xpert MTB/RIF assay for
investigation of patients suspected of having tuberculosis (TB). However, its utility for routine …

Detection of Mycobacterium tuberculosis antigens in urine is attractive as a potential means
of diagnosing tuberculosis (TB) regardless of the anatomical site of disease. The most …

Objective To assess the yield of finding additional TB or diabetes mellitus (DM) cases
through systematic screening and to determine the effectiveness of preventive TB therapy in …

Background We previously reported that one-third of HIV-positive adults requiring medical
admission to a South African district hospital had laboratory-confirmed tuberculosis (TB) and …