Oxidative stress (OS) due to an imbalance between reactive oxygen species (ROS) and
antioxidants has been established as an important factor that can negatively affect the …

BACKGROUND In a growth phase occurring during most of folliculogenesis, the oocyte
produces and accumulates molecules and organelles that are fundamental for the …

Advances in metabolomics have deepened our understanding of the roles that specific
modes of metabolism play in programming stem cell fates. Here, we review recent …

Recent advances in metabolomics and computational analysis have deepened our
appreciation for the role of specific metabolic pathways in dictating cell fate. Once thought to …

Reactive oxygen species and oxidative stress are closely associated with various
pathologies such as neurodegenerative diseases, ageing and male infertility. Hence …

BACKGROUND Mitochondria are multitasking organelles involved in ATP synthesis,
reactive oxygen species (ROS) production, calcium signalling and apoptosis; and …

This review considers how our understanding of preimplantation embryo metabolism has
progressed since the pioneering work on this topic in the late 1960s and early 1970s …

Contents While much is known about the metabolism of exogenous nutrients such as
glucose, lactate, pyruvate, amino acids by oocytes and pre‐implantation mammalian …

Abstract BACKGROUND Mitochondrial DNA (mtDNA) encodes key proteins associated with
the process of oxidative phosphorylation. Defects to mtDNA cause severe disease …

The first edition of the Textbook of Assisted Reproductive Techniques was published in
2001. As the textbook now enters its sixth edition, some 45 years since the birth of Louise …