Vaccine adjuvants: mechanisms and platforms

T Zhao, Y Cai, Y Jiang, X He, Y Wei, Y Yu… - Signal transduction and …, 2023 - nature.com
Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …

Translational applications of hydrogels

S Correa, AK Grosskopf, H Lopez Hernandez… - Chemical …, 2021 - ACS Publications
Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

Designing spatial and temporal control of vaccine responses

GA Roth, VCTM Picece, BS Ou, W Luo… - Nature Reviews …, 2022 - nature.com
Vaccines are the key technology to combat existing and emerging infectious diseases.
However, increasing the potency, quality and durability of the vaccine response remains a …

Recent applications of immunomodulatory biomaterials for disease immunotherapy

H Dai, Q Fan, C Wang - Exploration, 2022 - Wiley Online Library
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …

Tailoring materials for modulation of macrophage fate

J Li, X Jiang, H Li, M Gelinsky, Z Gu - Advanced Materials, 2021 - Wiley Online Library
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …

Generation of functionally distinct T-cell populations by altering the viscoelasticity of their extracellular matrix

K Adu-Berchie, Y Liu, DKY Zhang… - Nature biomedical …, 2023 - nature.com
The efficacy of adoptive T-cell therapies largely depends on the generation of T-cell
populations that provide rapid effector function and long-term protective immunity. Yet it is …

[HTML][HTML] Immunomodulatory bioactive glasses for tissue regeneration

K Zheng, W Niu, B Lei, AR Boccaccini - Acta Biomaterialia, 2021 - Elsevier
The regulatory functions of the immune response in tissue healing, repair, and regeneration
have been evidenced in the last decade. Immune cells play central roles in immune …

Bioadhesive injectable hydrogel with phenolic carbon quantum dot supported Pd single atom nanozymes as a localized immunomodulation niche for cancer catalytic …

H He, Z Fei, T Guo, Y Hou, D Li, K Wang, F Ren, K Fan… - Biomaterials, 2022 - Elsevier
Immunotherapy is a powerful way to treat cancer, however, systemic treatment-associated
adverse effects remain a major concern. In this study, a bioadhesive injectable hydrogel is …

[HTML][HTML] Biomaterials to enhance stem cell transplantation

BN Kharbikar, P Mohindra, TA Desai - Cell Stem Cell, 2022 - cell.com
The successful transplantation of stem cells has the potential to transform regenerative
medicine approaches and open promising avenues to repair, replace, and regenerate …

Harnessing 3D in vitro systems to model immune responses to solid tumours: a step towards improving and creating personalized immunotherapies

Z Zhou, Y Pang, J Ji, J He, T Liu, L Ouyang… - Nature Reviews …, 2024 - nature.com
In vitro 3D models are advanced biological tools that have been established to overcome
the shortcomings of oversimplified 2D cultures and mouse models. Various in vitro 3D …