[HTML][HTML] The epigenetic role of vitamin C in neurodevelopment

SJ Coker, CC Smith-Díaz, RM Dyson… - International Journal of …, 2022 - mdpi.com
The maternal diet during pregnancy is a key determinant of offspring health. Early studies
have linked poor maternal nutrition during gestation with a propensity for the development of …

Effect of aberrant DNA methylation on cancer stem cell properties

Z Mazloumi, R Farahzadi, A Rafat, KD Asl… - … and molecular pathology, 2022 - Elsevier
DNA methylation, as an epigenetic mechanism, occurs by adding a methyl group of
cytosines in position 5 by DNA methyltransferases and has essential roles in cellular …

Metals exposures and DNA methylation: current evidence and future directions

ER Elkin, C Higgins, MT Aung, KM Bakulski - Current environmental health …, 2022 - Springer
Abstract Purpose of the Review Exposure to essential and non-essential metals is
widespread. Metals exposure is linked to epigenetic, particularly DNA methylation …

[HTML][HTML] Factors regulating the activity of LINE1 retrotransposons

MS Protasova, TV Andreeva, EI Rogaev - Genes, 2021 - mdpi.com
LINE-1 (L1) is a class of autonomous mobile genetic elements that form somatic mosaicisms
in various tissues of the organism. The activity of L1 retrotransposons is strictly controlled by …

Gestational exposure to perfluoroalkyl substances is associated with placental DNA methylation and birth size

H Wang, W Li, J Yang, Y Wang, H Du, M Han… - Science of The Total …, 2023 - Elsevier
DNA methylation is one potential mechanism for the effects of gestational exposure to
perfluoroalkyl substances (PFASs) on fetal growth. We investigated 180 pregnant women …

Mechanisms of human DNA methylation, alteration of methylation patterns in physiological processes and oncology

A Sergeeva, K Davydova, A Perenkov, M Vedunova - Gene, 2023 - Elsevier
DNA methylation is one of the epigenetic modifications of the genome, the essence of which
is the attachment of a methyl group to nitrogenous bases. In the eukaryote genome, cytosine …

[HTML][HTML] Epigenetic effect of maternal methyl-group donor intake on offspring's health and disease

S Bokor, RA Vass, S Funke, T Ertl, D Molnár - Life, 2022 - mdpi.com
Maternal exposure to some dietary and environmental factors during embryonic
development can affect offspring's phenotype and, furthermore, the risk of developing …

Micronutrient imbalance and common phenotypes in neural tube defects

AD Kakebeen, L Niswander - genesis, 2021 - Wiley Online Library
Neural tube defects (NTDs) are among the most common birth defects, with a prevalence of
close to 19 per 10,000 births worldwide. The etiology of NTDs is complex involving the …

Mitigating the detrimental developmental impact of early fetal alcohol exposure using a maternal methyl donor‐enriched diet

M Breton‐Larrivée, E Elder, LM Legault… - The FASEB …, 2023 - Wiley Online Library
Fetal alcohol exposure at any stage of pregnancy can lead to fetal alcohol spectrum disorder
(FASD), a group of life‐long conditions characterized by congenital malformations, as well …

[HTML][HTML] Effect of prenatal ambient temperature on the performance physiological parameters, and oxidative metabolism of Japanese quail (Coturnix coturnix japonica …

TP Santana, E Gasparino, A de Souza Khatlab… - Scientific Reports, 2021 - nature.com
A strategy to mitigate the negative effects of stress on animals is to enhance their ability to
beneficially respond to stressful conditions. This study aimed to assess whether prenatal …