Celiac disease
C Catassi, A Fasano - Gluten-free cereal products and beverages, 2008 - Elsevier
Publisher Summary Celiac disease is an immune-mediated enteropathy triggered by the
ingestion of gluten in genetically susceptible individuals. The major predisposing genes are …
ingestion of gluten in genetically susceptible individuals. The major predisposing genes are …
Ancient genomes from present-day France unveil 7,000 years of its demographic history
S Brunel, EA Bennett, L Cardin… - Proceedings of the …, 2020 - National Acad Sciences
Genomic studies conducted on ancient individuals across Europe have revealed how
migrations have contributed to its present genetic landscape, but the territory of present-day …
migrations have contributed to its present genetic landscape, but the territory of present-day …
The impact of genome‐wide association studies on the pathophysiology and therapy of cardiovascular disease
Cardiovascular diseases are leading causes for death worldwide. Genetic disposition jointly
with traditional risk factors precipitates their manifestation. Whereas the implications of a …
with traditional risk factors precipitates their manifestation. Whereas the implications of a …
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium
Measurements of erythrocytes within the blood are important clinical traits and can indicate
various hematological disorders. We report here genome-wide association studies (GWAS) …
various hematological disorders. We report here genome-wide association studies (GWAS) …
Celiac disease: an immunological jigsaw
B Meresse, G Malamut, N Cerf-Bensussan - Immunity, 2012 - cell.com
Celiac disease (CD) is a chronic enteropathy induced by dietary gluten in genetically
predisposed people. The keystone of CD pathogenesis is an adaptive immune response …
predisposed people. The keystone of CD pathogenesis is an adaptive immune response …
Mechanisms by which gut microorganisms influence food sensitivities
Finely tuned mechanisms enable the gastrointestinal tract to break down dietary
components into nutrients without mounting, in the majority of cases, a dysregulated immune …
components into nutrients without mounting, in the majority of cases, a dysregulated immune …
The duodenal microbiota composition of adult celiac disease patients is associated with the clinical manifestation of the disease
P Wacklin, K Kaukinen, E Tuovinen… - Inflammatory bowel …, 2013 - academic.oup.com
Background Celiac disease is classically manifested in the gastrointestinal (GI) tract but
extraintestinal symptoms, such as dermatitis herpetiformis (DH), are also common. Besides …
extraintestinal symptoms, such as dermatitis herpetiformis (DH), are also common. Besides …
Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk
S Raychaudhuri, BP Thomson, EF Remmers, S Eyre… - Nature …, 2009 - nature.com
To discover new rheumatoid arthritis (RA) risk loci, we systematically examined 370 SNPs
from 179 independent loci with P< 0.001 in a published meta-analysis of RA genome-wide …
from 179 independent loci with P< 0.001 in a published meta-analysis of RA genome-wide …
Development of autoantibodies precedes clinical manifestations of autoimmune diseases: a comprehensive review
WT Ma, C Chang, ME Gershwin, ZX Lian - Journal of autoimmunity, 2017 - Elsevier
The etiology of autoimmune diseases is due to a combination of genetic predisposition and
environmental factors that alter the expression of immune regulatory genes through various …
environmental factors that alter the expression of immune regulatory genes through various …
Progress and challenges in genome-wide association studies in humans
P Donnelly - Nature, 2008 - nature.com
After more than a decade of hope and hype, researchers are finally making inroads into
understanding the genetic basis of many common human diseases. The use of genome …
understanding the genetic basis of many common human diseases. The use of genome …