Crohn's disease (CD) and celiac disease (CelD) are chronic intestinal inflammatory
diseases, involving genetic and environmental factors in their pathogenesis. The two …

Celiac disease (CD) is an increasingly common disease of the small intestine that occurs in
genetically susceptible subjects by ingestion of cereal gluten proteins. Gluten is highly …

An agenda for personalized medicine | Nature Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

The NOD-like receptor (NLR) family members are cytosolic sensors of microbial components
and danger signals. A subset of NLRs control inflammasome assembly that results in …

Eosinophilic esophagitis is a recently recognized but expanding disorder characterized by
antigen-driven eosinophil accumulation in the esophagus. Symptoms frequently mimic those …

Coeliac disease is an immune‐mediated disease caused by ingestion of gluten in
genetically susceptible individuals. Coeliac disease has been thought to affect mainly …

Even though heritability estimates suggest that the risk of asthma, hay fever and eczema is
largely due to genetic factors, previous studies have not explained a large part of the …

Autoimmune diseases occur when an individual's own immune system attacks and destroys
his or her healthy cells and tissues. Although it is clear that environmental stimuli can …

From epidemiological data, based on concordance data in family studies, via linkage
analysis to genome-wide association studies, we and others have accumulated robust …

Background While gluten‐free diet is an effective treatment for coeliac disease, the need for
and goals of long‐term management of patients are poorly defined. Aim To review …