Roles of transposable elements in the regulation of mammalian transcription
Transposable elements (TEs) comprise about half of the mammalian genome. TEs often
contain sequences capable of recruiting the host transcription machinery, which they use to …
contain sequences capable of recruiting the host transcription machinery, which they use to …
[HTML][HTML] Taming transposable elements in vertebrates: from epigenetic silencing to domestication
Transposable element (TE)-derived sequences are ubiquitous in most eukaryotic genomes
known to date. Because their expression and mobility can lead to genomic instability …
known to date. Because their expression and mobility can lead to genomic instability …
[HTML][HTML] Transposable elements as essential elements in the control of gene expression
A Gebrie - Mobile DNA, 2023 - Springer
Interspersed repetitions called transposable elements (TEs), commonly referred to as mobile
elements, make up a significant portion of the genomes of higher animals. TEs contribute in …
elements, make up a significant portion of the genomes of higher animals. TEs contribute in …
Recurrent evolution of vertebrate transcription factors by transposase capture
RL Cosby, J Judd, R Zhang, A Zhong, N Garry… - Science, 2021 - science.org
INTRODUCTION How novel protein architectures evolve remains poorly understood. The
rearrangement of domains with preexisting functions into new composite architectures …
rearrangement of domains with preexisting functions into new composite architectures …
TFs for TEs: the transcription factor repertoire of mammalian transposable elements
C Hermant, ME Torres-Padilla - Genes & development, 2021 - genesdev.cshlp.org
Transposable elements (TEs) are genetic elements capable of changing position within the
genome. Although their mobilization can constitute a threat to genome integrity, nearly half …
genome. Although their mobilization can constitute a threat to genome integrity, nearly half …
[HTML][HTML] Tissue-specific usage of transposable element-derived promoters in mouse development
Abstract Background Transposable elements (TEs) are a significant component of
eukaryotic genomes and play essential roles in genome evolution. Mounting evidence …
eukaryotic genomes and play essential roles in genome evolution. Mounting evidence …
[HTML][HTML] Role of transposable elements in gene regulation in the human genome
Transposable elements (TEs), also known as mobile elements (MEs), are interspersed
repeats that constitute a major fraction of the genomes of higher organisms. As one of their …
repeats that constitute a major fraction of the genomes of higher organisms. As one of their …
[HTML][HTML] DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumor immunotolerance
F D'anna, L Van Dyck, J Xiong, H Zhao, RV Berrens… - Genome biology, 2020 - Springer
Background Hypoxia is pervasive in cancer and other diseases. Cells sense and adapt to
hypoxia by activating hypoxia-inducible transcription factors (HIFs), but it is still an …
hypoxia by activating hypoxia-inducible transcription factors (HIFs), but it is still an …
[HTML][HTML] Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis
The novel betacoronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
caused a worldwide pandemic (COVID-19) after emerging in Wuhan, China. Here we …
caused a worldwide pandemic (COVID-19) after emerging in Wuhan, China. Here we …
AGO2 silences mobile transposons in the nucleus of quiescent cells
Abstract Argonaute 2 (AGO2) is a cytoplasmic component of the miRNA pathway, with
essential roles in development and disease. Yet little is known about its regulation in vivo …
essential roles in development and disease. Yet little is known about its regulation in vivo …