Metabolic messengers: ceramides

SA Summers, B Chaurasia, WL Holland - Nature metabolism, 2019 - nature.com
Ceramides are products of metabolism that accumulate in individuals with obesity or
dyslipidaemia and alter cellular processes in response to fuel surplus. Their actions, when …

An overview of the modulatory effects of oleic acid in health and disease

H Sales-Campos, P Reis de Souza… - Mini reviews in …, 2013 - ingentaconnect.com
Evidences in the last years have showed the effects of oleic acid (OA) in human health and
disease. Olive oil, rich in oleic acid, is supposed to present modulatory effects in a wide …

Targeting a ceramide double bond improves insulin resistance and hepatic steatosis

B Chaurasia, TS Tippetts, R Mayoral Monibas, J Liu… - Science, 2019 - science.org
Ceramides contribute to the lipotoxicity that underlies diabetes, hepatic steatosis, and heart
disease. By genetically engineering mice, we deleted the enzyme dihydroceramide …

Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity

E Fabbrini, F Magkos, BS Mohammed… - Proceedings of the …, 2009 - National Acad Sciences
Visceral adipose tissue (VAT) is an important risk factor for obesity-related metabolic
disorders. Therefore, a reduction in VAT has become a key goal in obesity management …

Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease

JFC Glatz, JJFP Luiken, A Bonen - Physiological reviews, 2010 - journals.physiology.org
Long-chain fatty acids and lipids serve a wide variety of functions in mammalian
homeostasis, particularly in the formation and dynamic properties of biological membranes …

[PDF][PDF] Cell culture media: a review

M Arora - Mater methods, 2013 - researchgate.net
Types of Cell Culture Media Animal cells can be cultured either using a completely natural
medium or an artificial/synthetic medium along with some natural products. Natural Media …

Albumin and mammalian cell culture: implications for biotechnology applications

GL Francis - Cytotechnology, 2010 - Springer
Albumin has a long historical involvement in design of media for the successful culture of
mammalian cells, in both the research and commercial fields. The potential application of …

Cellular fatty acid uptake: a pathway under construction

X Su, NA Abumrad - Trends in Endocrinology & Metabolism, 2009 - cell.com
Membrane uptake of long-chain fatty acids (FAs) is the first step in cellular FA utilization and
a point of metabolic regulation. CD36 facilitates a major fraction of FA uptake by key tissues …

Ceramide as a mediator of non-alcoholic fatty liver disease and associated atherosclerosis

T Kasumov, L Li, M Li, K Gulshan, JP Kirwan, X Liu… - PloS one, 2015 - journals.plos.org
Cardiovascular disease (CVD) is a serious comorbidity in nonalcoholic fatty liver disease
(NAFLD). Since plasma ceramides are increased in NAFLD and sphingomyelin, a ceramide …

Cholesterol–the devil you know; ceramide–the devil you don't

TS Tippetts, WL Holland, SA Summers - Trends in pharmacological …, 2021 - cell.com
Ectopic lipids play a key role in numerous pathologies, including heart disease, stroke, and
diabetes. Of all the lipids studied, perhaps the most well understood is cholesterol, a widely …