The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …

DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Coagulopathy and fibrinolytic pathophysiology in COVID-19 and SARS-CoV-2 vaccination

S Yamada, H Asakura - International Journal of Molecular Sciences, 2022 - mdpi.com
Coronavirus Disease 2019 (COVID-19) is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and is frequently complicated by thrombosis. In some cases of …

Flavonoids as a therapeutical option for the treatment of thrombotic complications associated with COVID‐19

JP Quintal Martinez… - Phytotherapy …, 2023 - Wiley Online Library
The SARS‐CoV‐2 outbreak has been one of the largest public health crises globally, while
thrombotic complications have emerged as an important factor contributing to mortality …

[HTML][HTML] Impact of COVID‐19 on thrombus composition and response to thrombolysis: insights from a monocentric cohort population of COVID‐19 patients with acute …

JP Desilles, MS Nomenjanahary, A Consoli… - Journal of Thrombosis …, 2022 - Elsevier
Background Resistance to fibrinolysis, levels of procoagulant/antifibrinolytic neutrophil
extracellular traps (NETs), and the severity of acute ischemic stroke (AIS) are increased by …

Viscoelastic testing: Critical appraisal of new methodologies and current literature

GD Wool, T Carll - International Journal of Laboratory …, 2023 - Wiley Online Library
Abstract United States Food and Drug Administration (FDA)‐approved viscoelastic testing
(VET) methodologies have significantly changed in the last 10 years, with the availability of …

[HTML][HTML] COVID‐19 patient fibrinogen produces dense clots with altered polymerization kinetics, partially explained by increased sialic acid

N Moiseiwitsch, N Zwennes, F Szlam… - Journal of Thrombosis …, 2022 - Elsevier
Background Thrombogenicity is a known complication of COVID‐19, resulting from SARS‐
CoV‐2 infection, with significant effects on morbidity and mortality. Objective We aimed to …

Four years into the pandemic, managing COVID-19 patients with acute coagulopathy: what have we learned?

T Iba, JH Levy, CL Maier, JM Connors, M Levi - Journal of Thrombosis and …, 2024 - Elsevier
Coagulopathy alongside micro-and macrovascular thrombotic events were frequent
characteristics of patients presenting with acute COVID-19 during the initial stages of the …

Fibrinolysis in COVID-19: impact on Clot Lysis and Modulation of Inflammation

MA Sugimoto, LO Perucci, LP Tavares… - Current Drug …, 2022 - ingentaconnect.com
COVID-19 is a multisystem disease caused by SARS-CoV-2 and is associated with an
imbalance between the coagulation and fibrinolytic systems. Overall, hypercoagulation …

Role of Fibrinolysis in the Management of Patients with COVID-19 and Thromboembolic Complications: A Review

P Zając, K Kaziród-Wolski, I Oleś, J Sielski… - Journal of …, 2022 - mdpi.com
An impaired fibrinolytic process has been demonstrated in patients infected with SARS-CoV-
2, including those in severe or critical condition. Disruption of fibrinolysis leads to fibrin …

Case Report: First attempt by off-label use of tenecteplase to treat acute extensive portal venous system thrombosis

Q Li, Y Piao, Y Zhang, X Qi - Frontiers in Cardiovascular Medicine, 2024 - frontiersin.org
Acute extensive portal venous system thrombosis (PVST) can cause lethal complications.
Herein, we have for the first time reported the use of anticoagulation combined with systemic …