[HTML][HTML] Cartilage tissue engineering: From proinflammatory and anti‑inflammatory cytokines to osteoarthritis treatments

S Liu, Z Deng, K Chen, S Jian… - Molecular …, 2022 - spandidos-publications.com
Osteoarthritis (OA), one of the most common joint diseases, is characterized by fibrosis,
rhagadia, ulcers and attrition of articular cartilage due to a number of factors. The etiology of …

Print me an organ! Why we are not there yet

WL Ng, CK Chua, YF Shen - Progress in Polymer Science, 2019 - Elsevier
Bioprinting offers a highly-automated and advanced manufacturing platform that facilitates
the deposition of bio-inks (living cells, biomaterials and growth factors) in a scalable and …

Injectable immunomodulation-based porous chitosan microspheres/HPCH hydrogel composites as a controlled drug delivery system for osteochondral regeneration

X Ji, H Shao, X Li, MW Ullah, G Luo, Z Xu, L Ma, X He… - Biomaterials, 2022 - Elsevier
The inappropriate regenerated fibrous cartilage and subchondral bone of the injured
chondral defect ultimately cause degeneration of the regenerated cartilage, which …

[HTML][HTML] Mesenchymal stem cell-based therapy of osteoarthritis: Current knowledge and future perspectives

CR Harrell, BS Markovic, C Fellabaum… - Biomedicine & …, 2019 - Elsevier
Osteoarthritis (OA) is a chronic, prevalent, debilitating joint disease characterized by
progressive cartilage degradation, subchondral bone remodeling, bone marrow lesions …

[HTML][HTML] Integrated gradient tissue-engineered osteochondral scaffolds: Challenges, current efforts and future perspectives

X Niu, N Li, Z Du, X Li - Bioactive Materials, 2023 - Elsevier
The osteochondral defect repair has been most extensively studied due to the rising
demand for new therapies to diseases such as osteoarthritis. Tissue engineering has been …

[HTML][HTML] Review of synthetic and hybrid scaffolds in cartilage tissue engineering

M Wasyłeczko, W Sikorska, A Chwojnowski - Membranes, 2020 - mdpi.com
Cartilage tissue is under extensive investigation in tissue engineering and regenerative
medicine studies because of its limited regenerative potential. Currently, many scaffolds are …

[HTML][HTML] 3D printed hydrogel for articular cartilage regeneration

X Yang, S Li, Y Ren, L Qiang, Y Liu, J Wang… - Composites Part B …, 2022 - Elsevier
Tissue engineering is a promising strategy for damaged cartilage tissue repair. Three-
dimensional (3D) printed hydrogel exhibits great potential in cartilage tissue engineering for …

[HTML][HTML] Exosomes produced from 3D cultures of umbilical cord mesenchymal stem cells in a hollow-fiber bioreactor show improved osteochondral regeneration …

L Yan, X Wu - Cell biology and toxicology, 2020 - Springer
Animal and clinical studies have shown that mesenchymal stem cells (MSCs) play an
important role in cartilage repair. The therapeutic effect of mesenchymal stem cells based …

Growth factor and its polymer scaffold-based delivery system for cartilage tissue engineering

L Chen, J Liu, M Guan, T Zhou, X Duan… - International journal of …, 2020 - Taylor & Francis
The development of biomaterials, stem cells and bioactive factors has led to cartilage tissue
engineering becoming a promising tactic to repair cartilage defects. Various polymer three …

Intra-articular targeting of nanomaterials for the treatment of osteoarthritis

S Brown, S Kumar, B Sharma - Acta biomaterialia, 2019 - Elsevier
Osteoarthritis is a prevalent and debilitating disease that involves pathological contributions
from numerous joint tissues and cells. The joint is a challenging arena for drug delivery …